Anatomy & Physiology
5th Edition
ISBN: 9780321861580
Author: Marieb, Elaine N.
Publisher: Pearson College Div
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Chapter 6, Problem 3CYU
Cartilage grows by interstitial growth. What does this mean?
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Case Study—Ella
Review the case study and then answer Parts A through F.
Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch.
Categories of Sandwich Options (Top of the screen)
Breads
Spreads
Cheeses
Vegetables
Proteins
Specific food items to select
White Bread 6-inches
Honey Mustard
Provolone
LettuceTomatoBell Peppers
Turkey
Part A - Reading Nutrition Facts Panels for Total Kilocalories
How many total kilocalories are in Ella’s sandwich?
_____…
Chapter 6 Solutions
Anatomy & Physiology
Ch. 6 - Which type of cartilage is most plentiful in the...Ch. 6 - What two body structures contain flexible elastic...Ch. 6 - Cartilage grows by interstitial growth. What does...Ch. 6 - What are the components of the axial skeleton?Ch. 6 - Contrast the general function of the axial...Ch. 6 - What bone class do the ribs and skull bones fall...Ch. 6 - What is the functional relationship between...Ch. 6 - What two types of substances are stored in bone...Ch. 6 - Describe two functions of a bones marrow cavities.Ch. 6 - Are crests, tubercles, and spines bony projections...
Ch. 6 - How does the structure of compact bone differ from...Ch. 6 - Which membrane lines the internal canals and...Ch. 6 - Which component of bone-organic or inorganic-makes...Ch. 6 - Prob. 14CYUCh. 6 - Bones dont begin with bone tissue. What do they...Ch. 6 - When describing endochondral ossification, some...Ch. 6 - Where is the primary ossification center located...Ch. 6 - As a long bone grows in length, what is happening...Ch. 6 - If osteoclasts in a long bone are more active than...Ch. 6 - Which stimulus-PTH (a hormone) or mechanical...Ch. 6 - How does an open fracture differ from a closed...Ch. 6 - How do bone growth and bone remodeling differ?Ch. 6 - Which bone disorder is characterized by excessive...Ch. 6 - What are three measures that may help to maintain...Ch. 6 - Prob. 25CYUCh. 6 - Which is a function of the skeletal system? (a)...Ch. 6 - A bone with approximately the same width, length,...Ch. 6 - The shaft of a long bone is properly called the...Ch. 6 - Sites of hematopoiesis include all but (a) red...Ch. 6 - An osteon has (a) a central canal carrying blood...Ch. 6 - Prob. 6RQCh. 6 - The flat bones of the skull develop from (a)...Ch. 6 - The remodeling of bone is a function of which...Ch. 6 - Bone remodeling in adults is regulated and...Ch. 6 - Prob. 10RQCh. 6 - Wolffs law is concerned with (a) calcium...Ch. 6 - Prob. 12RQCh. 6 - Prob. 13RQCh. 6 - Prob. 14RQCh. 6 - Compare bone to cartilage tissue relative to its...Ch. 6 - Describe in proper sequence the events of...Ch. 6 - Osteocytes residing in lacunae of osteons of...Ch. 6 - As we grow, our long bones increase in diameter,...Ch. 6 - Describe the process of new bone formation in an...Ch. 6 - Compare and contrast controls of bone remodeling...Ch. 6 - Yolanda is asked to review a bone slide that her...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...
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- Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions Calculate these : a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)arrow_forwardIn a population of Jackalopes (pictured below), horn length will vary between 0.5 and 2 feet, with the mean length somewhere around 1.05 feet. You pick Jackalopes that have horn lengths around 1.75 feet to breed as this appears to be the optimal length for battling other Jackalopes for food. After a round of breeding, you measure the offsprings' mean horn length is 1.67. What is the heritability of horns length (h2)? Is Jackalope horn length a heritable trait? (4 pts)? 12pt v R Paragraph V BIU A श्र > Barrow_forwardThere are many differences between DNA replication happening during mitosis in a Douglas fir tree growing in the Oregon Cascade Mountains and DNA replication happening during a PCR reaction in a forestry research lab at Oregon State University where the laboratory is amplifying a Simple Sequence Repeat. Complete the following table that compares the two DNA replication events in terms of the primers, the nucleotides, the polymerase, and the target sequence. Additionally, give a general value for the number of copies of the template DNA after one S phase in one cell and after the lab has completed the PCR reaction. Tree SSR Type your answer here: Primers Nucleotides Polymerase Target sequence Number of copiesarrow_forward
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