Anatomy & Physiology
5th Edition
ISBN: 9780321861580
Author: Marieb, Elaine N.
Publisher: Pearson College Div
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 6, Problem 19RQ
Describe the process of new bone formation in an adult bone. Use the terms osteoid seam and calcification front in your discussion.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine:
(a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip
MAKE SURE ANSWERS HAVE UNITS if appropriate.
SHOW ALL WORK, including equation used, variables used and each step to your solution.
2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…
The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?
Chapter 6 Solutions
Anatomy & Physiology
Ch. 6 - Which type of cartilage is most plentiful in the...Ch. 6 - What two body structures contain flexible elastic...Ch. 6 - Cartilage grows by interstitial growth. What does...Ch. 6 - What are the components of the axial skeleton?Ch. 6 - Contrast the general function of the axial...Ch. 6 - What bone class do the ribs and skull bones fall...Ch. 6 - What is the functional relationship between...Ch. 6 - What two types of substances are stored in bone...Ch. 6 - Describe two functions of a bones marrow cavities.Ch. 6 - Are crests, tubercles, and spines bony projections...
Ch. 6 - How does the structure of compact bone differ from...Ch. 6 - Which membrane lines the internal canals and...Ch. 6 - Which component of bone-organic or inorganic-makes...Ch. 6 - Prob. 14CYUCh. 6 - Bones dont begin with bone tissue. What do they...Ch. 6 - When describing endochondral ossification, some...Ch. 6 - Where is the primary ossification center located...Ch. 6 - As a long bone grows in length, what is happening...Ch. 6 - If osteoclasts in a long bone are more active than...Ch. 6 - Which stimulus-PTH (a hormone) or mechanical...Ch. 6 - How does an open fracture differ from a closed...Ch. 6 - How do bone growth and bone remodeling differ?Ch. 6 - Which bone disorder is characterized by excessive...Ch. 6 - What are three measures that may help to maintain...Ch. 6 - Prob. 25CYUCh. 6 - Which is a function of the skeletal system? (a)...Ch. 6 - A bone with approximately the same width, length,...Ch. 6 - The shaft of a long bone is properly called the...Ch. 6 - Sites of hematopoiesis include all but (a) red...Ch. 6 - An osteon has (a) a central canal carrying blood...Ch. 6 - Prob. 6RQCh. 6 - The flat bones of the skull develop from (a)...Ch. 6 - The remodeling of bone is a function of which...Ch. 6 - Bone remodeling in adults is regulated and...Ch. 6 - Prob. 10RQCh. 6 - Wolffs law is concerned with (a) calcium...Ch. 6 - Prob. 12RQCh. 6 - Prob. 13RQCh. 6 - Prob. 14RQCh. 6 - Compare bone to cartilage tissue relative to its...Ch. 6 - Describe in proper sequence the events of...Ch. 6 - Osteocytes residing in lacunae of osteons of...Ch. 6 - As we grow, our long bones increase in diameter,...Ch. 6 - Describe the process of new bone formation in an...Ch. 6 - Compare and contrast controls of bone remodeling...Ch. 6 - Yolanda is asked to review a bone slide that her...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...Ch. 6 - Remember Mrs. DeStephano? When we last heard about...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- View History Bookmarks Window Help Quarter cements ents ons (17) YouTube Which amino acids would you expect to find marked on the alpha helix? canvas.ucsc.edu ucsc Complaint and Grievance Process - Academic Personnel pach orations | | | | | | | | | | | | | | | | 000000 000000000 | | | | | | | | | | | | | | | | | | | | | | 00000000 scope vious De 48 12.415 KATPM FEB 3 F1 F2 80 F3 a F4 F5 2 # 3 $ 85 % tv N A の Mon Feb 3 10:24 PM Lipid bilayer Submit Assignment Next > ZOOM < Å DII 8 བ བ F6 16 F7 F8 F9 F10 34 F11 F12 & * ( 6 7 8 9 0 + 11 WERTY U { 0 } P deletearrow_forwardDifferent species or organisms research for ecologyarrow_forwardWhat is the result of the following gram stain: positive ○ capsulated ○ acid-fast ○ negativearrow_forward
- What type of stain is the image below: capsule stain endospore stain gram stain negative stain ASM MicrobeLibrary.org Keplingerarrow_forwardWhat is the result of the acid-fast stain below: Stock Images by Getty Images by Getty Images by Getty Images by Getty Image Getty Images St Soy Getty Images by Getty Images by Getty Images Joy Getty encapsulated O endosporulating negative ○ positivearrow_forwardYou have a stock vial of diligence 75mg in 3ml and need to draw up a dose of 50mg for your patient.how many mls should you draw up to give this dosearrow_forward
- You are recquired to administer 150mg hydrocortisone intravenously,how many mls should you give?(stock =hydrocortisone 100mg in 2mls)arrow_forwardIf someone was working with a 50 MBq F-18 source, what would be the internal and external dose consequences?arrow_forwardWe will be starting a group project next week where you and your group will research and ultimately present on a current research article related to the biology of a pathogen that infects humans. The article could be about the pathogen itself, the disease process related to the pathogen, the immune response to the pathogen, vaccines or treatments that affect the pathogen, or other biology-related study about the pathogen. I recommend that you choose a pathogen that is currently interesting to researchers, so that you will be able to find plenty of articles about it. Avoid choosing a historical disease that no longer circulates. List 3 possible pathogens or diseases that you might want to do for your group project.arrow_forward
- not use ai pleasearrow_forwardDNK dagi nukleotidlar va undan sintezlangan oqsildagi peptid boglar farqi 901 taga teng bo'lib undagi A jami H boglardan 6,5 marta kam bo'lsa DNK dagi jami H bog‘lar sonini topingarrow_forwardOne of the ways for a cell to generate ATP is through the oxidative phosphorylation. In oxidative phosphorylation 3 ATP are produced from every one NADH molecule. In respiration, every glucose molecule produces 10 NADH molecules. If a cell is growing on 5 glucose molecules, how much ATP can be produced using oxidative phosphorylation/aerobic respiration?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
Medical Terminology for Health Professions, Spira...Health & NutritionISBN:9781305634350Author:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. SchroederPublisher:Cengage Learning
Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
Medical Terminology for Health Professions, Spira...
Health & Nutrition
ISBN:9781305634350
Author:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder
Publisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
GCSE PE - ANTAGONISTIC MUSCLE ACTION - Anatomy and Physiology (Skeletal and Muscular System - 1.5); Author: igpe_complete;https://www.youtube.com/watch?v=6hm_9jQRoO4;License: Standard Youtube License