Biology
Biology
12th Edition
ISBN: 9781260494570
Author: Raven, Peter
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 6, Problem 2S

Phosphofructokinase functions to add a phosphate group to a molecule of fructose 6-phosphate. This enzyme functions early in glycolysis, an energy-yielding biochemical pathway discussed in chapter 7. The enzyme has an active site that binds fructose and ATP. An allosteric inhibitory site also binds ATP when cellular levels of ATP are very high.

a. Predict the rate of the reaction if the levels of cellular ATP are low.

b. Predict the rate of the reaction if levels of cellular ATP are very high.

c. Describe what is happening to the enzyme when levels of ATP are very high.

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