EBK PRINCIPLES OF ANATOMY AND PHYSIOLOG
16th Edition
ISBN: 9781119662686
Author: DERRICKSON
Publisher: VST
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Chapter 6, Problem 2CP
Describe the role of bones in blood cell production.
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Case Study—Ella
Review the case study and then answer Parts A through F.
Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch.
Categories of Sandwich Options (Top of the screen)
Breads
Spreads
Cheeses
Vegetables
Proteins
Specific food items to select
White Bread 6-inches
Honey Mustard
Provolone
LettuceTomatoBell Peppers
Turkey
Part A - Reading Nutrition Facts Panels for Total Kilocalories
How many total kilocalories are in Ella’s sandwich?
_____…
Chapter 6 Solutions
EBK PRINCIPLES OF ANATOMY AND PHYSIOLOG
Ch. 6 - How does the skeletal system function in support,...Ch. 6 - 2. Describe the role of bones in blood cell...Ch. 6 - Which bones contain red bone marrow?Ch. 6 - How do red bone marrow and yellow bone marrow...Ch. 6 - 5. Diagram the parts of a long bone, and list the...Ch. 6 - Why is bone considered a connective tissue?Ch. 6 - What factors contribute to the hardness and...Ch. 6 - 8. List the four types of cells in bone tissue and...Ch. 6 - What is the composition of the extracellular...Ch. 6 - Prob. 10CP
Ch. 6 - What is a bone scan and how is it used clinically?Ch. 6 - Prob. 12CPCh. 6 - Which part of a bone contains sensory nerves...Ch. 6 - Prob. 14CPCh. 6 - Prob. 15CPCh. 6 - 16. What are the major events of intramembranous...Ch. 6 - 17. Describe the zones of the epiphyseal (growth)...Ch. 6 - Explain how bone growth in length differs from...Ch. 6 - How could the metaphyseal area of a bone help...Ch. 6 - Define remodeling, and describe the roles of...Ch. 6 - Prob. 21CPCh. 6 - List the types of fractures and outline the four...Ch. 6 - 23. Define each of the common fractures.
Ch. 6 - 24. How do hormones act on bone to regulate...Ch. 6 - 25. How do mechanical stresses strengthen bone...Ch. 6 - Would children raised in space ever be able to...Ch. 6 - Prob. 27CPCh. 6 - Prob. 28CPCh. 6 - What changes occur in the organic part of bone...Ch. 6 - Prob. 1CTQCh. 6 - Prob. 2CTQCh. 6 - Astronauts in space exercise as part of their...
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