EBK HUMAN PHYSIOLOGY
EBK HUMAN PHYSIOLOGY
7th Edition
ISBN: 9780133983401
Author: Silverthorn
Publisher: YUZU
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Chapter 6, Problem 2CC

Which signal molecules listed in the previous question are transported through the circulatory system? Which are released by neurons?

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"One of the symmetry breaking events in mouse gastrulation requires the amplification of Nodal on the side of the embryo opposite to the Anterior Visceral Endoderm (AVE). Describe one way by which Nodal gets amplified in this region." My understanding of this is that there are a few ways nodal is amplified though I'm not sure if this is specifically occurs on the opposite side of the AVE.  1. pronodal cleaved by protease -> active nodal 2. Nodal -> BMP4 -> Wnt-> nodal 3. Nodal-> Nodal, Fox1 binding site  4. BMP4 on outside-> nodal  Are all of these occuring opposite to AVE?
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EBK HUMAN PHYSIOLOGY

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