The mother’s genotype in terms of the sickle cell gene and whether the mother is homozygous or heterozygous. Introduction: The disorders which are caused by a single mutant or defective gene are known as a single-gene disorder. The mutant gene may be present on an autosome or X chromosome. The defective gene may affect only one member of an autosomal gene pair or both pairs.

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Answer 1

Question

Chapter 6, Problem 1RE

A.

Summary Introduction

To determine: The mother’s genotype in terms of the sickle cell gene and whether the mother is homozygous or heterozygous.

Introduction: The disorders which are caused by a single mutant or defective gene are known as a single-gene disorder. The mutant gene may be present on an autosome or X chromosome. The defective gene may affect only one member of an autosomal gene pair or both pairs.

A.

Expert Solution

Explanation of Solution

The sickle cell anemia is a genetic disorder in which the shape or structure of the red blood cells is changed due to two abnormal genes of the β-globin gene, which is responsible for making hemoglobin. The shape of the blood cells is changed to a sickle-like shape. The genotype of a mother with sickle cell anemia will be Hb^SHb^S( Hb is for hemoglobin and S is for defective sickle cell gene). The mother is homozygous, which means that she will have the same alleles (Hb^SHb^S).

B.

Summary Introduction

To determine: The probability of their child having the disease or being a carrier of the sickle cell trait.

Introduction: The single gene defect follows the pattern of a mendelian pattern of inheritance and is known as Mendelian disorders. Sickle cell anemia is a blood-related disorder in which there is a decrease in healthy red blood cells.

B.

Expert Solution

Explanation of Solution

The sickle cell anemia is an inherited disorder that affects the hemoglobin molecule present in the red blood cell, responsible for carrying the oxygen throughout the body. The people with sickle cell anemia have an abnormal hemoglobin molecule S, which affects the shape of the red blood cell and convert it to a sickle shape.

The mother has sickle cell anemia with genotype Hb^SHb^S, whereas the father may be normal (Hb^AHb^A) or a carrier (Hb^AHb^A) of the trait. If the father is the carrier of the trait, then the chances of the child getting the disorder are 50%, and if the father is normal, then the next generation will be 100% carrier of the disorder.

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Answer 2

Question

Chapter 6, Problem 1RE

A.

Summary Introduction

To determine: The mother’s genotype in terms of the sickle cell gene and whether the mother is homozygous or heterozygous.

Introduction: The disorders which are caused by a single mutant or defective gene are known as a single-gene disorder. The mutant gene may be present on an autosome or X chromosome. The defective gene may affect only one member of an autosomal gene pair or both pairs.

A.

Expert Solution

Explanation of Solution

The sickle cell anemia is a genetic disorder in which the shape or structure of the red blood cells is changed due to two abnormal genes of the β-globin gene, which is responsible for making hemoglobin. The shape of the blood cells is changed to a sickle-like shape. The genotype of a mother with sickle cell anemia will be Hb^SHb^S( Hb is for hemoglobin and S is for defective sickle cell gene). The mother is homozygous, which means that she will have the same alleles (Hb^SHb^S).

B.

Summary Introduction

To determine: The probability of their child having the disease or being a carrier of the sickle cell trait.

Introduction: The single gene defect follows the pattern of a mendelian pattern of inheritance and is known as Mendelian disorders. Sickle cell anemia is a blood-related disorder in which there is a decrease in healthy red blood cells.

B.

Expert Solution

Explanation of Solution

The sickle cell anemia is an inherited disorder that affects the hemoglobin molecule present in the red blood cell, responsible for carrying the oxygen throughout the body. The people with sickle cell anemia have an abnormal hemoglobin molecule S, which affects the shape of the red blood cell and convert it to a sickle shape.

The mother has sickle cell anemia with genotype Hb^SHb^S, whereas the father may be normal (Hb^AHb^A) or a carrier (Hb^AHb^A) of the trait. If the father is the carrier of the trait, then the chances of the child getting the disorder are 50%, and if the father is normal, then the next generation will be 100% carrier of the disorder.

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Answer 3

Question

Chapter 6, Problem 1RE

A.

Summary Introduction

To determine: The mother’s genotype in terms of the sickle cell gene and whether the mother is homozygous or heterozygous.

Introduction: The disorders which are caused by a single mutant or defective gene are known as a single-gene disorder. The mutant gene may be present on an autosome or X chromosome. The defective gene may affect only one member of an autosomal gene pair or both pairs.

A.

Expert Solution

Explanation of Solution

The sickle cell anemia is a genetic disorder in which the shape or structure of the red blood cells is changed due to two abnormal genes of the β-globin gene, which is responsible for making hemoglobin. The shape of the blood cells is changed to a sickle-like shape. The genotype of a mother with sickle cell anemia will be Hb^SHb^S( Hb is for hemoglobin and S is for defective sickle cell gene). The mother is homozygous, which means that she will have the same alleles (Hb^SHb^S).

B.

Summary Introduction

To determine: The probability of their child having the disease or being a carrier of the sickle cell trait.

Introduction: The single gene defect follows the pattern of a mendelian pattern of inheritance and is known as Mendelian disorders. Sickle cell anemia is a blood-related disorder in which there is a decrease in healthy red blood cells.

B.

Expert Solution

Explanation of Solution

The sickle cell anemia is an inherited disorder that affects the hemoglobin molecule present in the red blood cell, responsible for carrying the oxygen throughout the body. The people with sickle cell anemia have an abnormal hemoglobin molecule S, which affects the shape of the red blood cell and convert it to a sickle shape.

The mother has sickle cell anemia with genotype Hb^SHb^S, whereas the father may be normal (Hb^AHb^A) or a carrier (Hb^AHb^A) of the trait. If the father is the carrier of the trait, then the chances of the child getting the disorder are 50%, and if the father is normal, then the next generation will be 100% carrier of the disorder.

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Answer 4

Question

Chapter 6, Problem 1RE

A.

Summary Introduction

To determine: The mother’s genotype in terms of the sickle cell gene and whether the mother is homozygous or heterozygous.

Introduction: The disorders which are caused by a single mutant or defective gene are known as a single-gene disorder. The mutant gene may be present on an autosome or X chromosome. The defective gene may affect only one member of an autosomal gene pair or both pairs.

A.

Expert Solution

Explanation of Solution

The sickle cell anemia is a genetic disorder in which the shape or structure of the red blood cells is changed due to two abnormal genes of the β-globin gene, which is responsible for making hemoglobin. The shape of the blood cells is changed to a sickle-like shape. The genotype of a mother with sickle cell anemia will be Hb^SHb^S( Hb is for hemoglobin and S is for defective sickle cell gene). The mother is homozygous, which means that she will have the same alleles (Hb^SHb^S).

B.

Summary Introduction

To determine: The probability of their child having the disease or being a carrier of the sickle cell trait.

Introduction: The single gene defect follows the pattern of a mendelian pattern of inheritance and is known as Mendelian disorders. Sickle cell anemia is a blood-related disorder in which there is a decrease in healthy red blood cells.

B.

Expert Solution

Explanation of Solution

The sickle cell anemia is an inherited disorder that affects the hemoglobin molecule present in the red blood cell, responsible for carrying the oxygen throughout the body. The people with sickle cell anemia have an abnormal hemoglobin molecule S, which affects the shape of the red blood cell and convert it to a sickle shape.

The mother has sickle cell anemia with genotype Hb^SHb^S, whereas the father may be normal (Hb^AHb^A) or a carrier (Hb^AHb^A) of the trait. If the father is the carrier of the trait, then the chances of the child getting the disorder are 50%, and if the father is normal, then the next generation will be 100% carrier of the disorder.

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Answer 5

Chapter 6, Problem 1RE

A.

Summary Introduction

To determine: The mother’s genotype in terms of the sickle cell gene and whether the mother is homozygous or heterozygous.

Introduction: The disorders which are caused by a single mutant or defective gene are known as a single-gene disorder. The mutant gene may be present on an autosome or X chromosome. The defective gene may affect only one member of an autosomal gene pair or both pairs.

A.

Expert Solution

Explanation of Solution

The sickle cell anemia is a genetic disorder in which the shape or structure of the red blood cells is changed due to two abnormal genes of the β-globin gene, which is responsible for making hemoglobin. The shape of the blood cells is changed to a sickle-like shape. The genotype of a mother with sickle cell anemia will be Hb^SHb^S( Hb is for hemoglobin and S is for defective sickle cell gene). The mother is homozygous, which means that she will have the same alleles (Hb^SHb^S).

B.

Summary Introduction

To determine: The probability of their child having the disease or being a carrier of the sickle cell trait.

Introduction: The single gene defect follows the pattern of a mendelian pattern of inheritance and is known as Mendelian disorders. Sickle cell anemia is a blood-related disorder in which there is a decrease in healthy red blood cells.

B.

Expert Solution

Explanation of Solution

The sickle cell anemia is an inherited disorder that affects the hemoglobin molecule present in the red blood cell, responsible for carrying the oxygen throughout the body. The people with sickle cell anemia have an abnormal hemoglobin molecule S, which affects the shape of the red blood cell and convert it to a sickle shape.

The mother has sickle cell anemia with genotype Hb^SHb^S, whereas the father may be normal (Hb^AHb^A) or a carrier (Hb^AHb^A) of the trait. If the father is the carrier of the trait, then the chances of the child getting the disorder are 50%, and if the father is normal, then the next generation will be 100% carrier of the disorder.

Answer 6

Chapter 6, Problem 1RE

A.

Summary Introduction

To determine: The mother’s genotype in terms of the sickle cell gene and whether the mother is homozygous or heterozygous.

Introduction: The disorders which are caused by a single mutant or defective gene are known as a single-gene disorder. The mutant gene may be present on an autosome or X chromosome. The defective gene may affect only one member of an autosomal gene pair or both pairs.

A.

Expert Solution

Explanation of Solution

The sickle cell anemia is a genetic disorder in which the shape or structure of the red blood cells is changed due to two abnormal genes of the β-globin gene, which is responsible for making hemoglobin. The shape of the blood cells is changed to a sickle-like shape. The genotype of a mother with sickle cell anemia will be Hb^SHb^S( Hb is for hemoglobin and S is for defective sickle cell gene). The mother is homozygous, which means that she will have the same alleles (Hb^SHb^S).

Answer 7

Chapter 6, Problem 1RE

A.

Summary Introduction

To determine: The mother’s genotype in terms of the sickle cell gene and whether the mother is homozygous or heterozygous.

Introduction: The disorders which are caused by a single mutant or defective gene are known as a single-gene disorder. The mutant gene may be present on an autosome or X chromosome. The defective gene may affect only one member of an autosomal gene pair or both pairs.

Answer 8

A.

Expert Solution

Explanation of Solution

The sickle cell anemia is a genetic disorder in which the shape or structure of the red blood cells is changed due to two abnormal genes of the β-globin gene, which is responsible for making hemoglobin. The shape of the blood cells is changed to a sickle-like shape. The genotype of a mother with sickle cell anemia will be Hb^SHb^S( Hb is for hemoglobin and S is for defective sickle cell gene). The mother is homozygous, which means that she will have the same alleles (Hb^SHb^S).

Answer 9

A.

Expert Solution

Answer 10

A.

Expert Solution

Answer 11

Expert Solution

Answer 12

B.

Summary Introduction

To determine: The probability of their child having the disease or being a carrier of the sickle cell trait.

Introduction: The single gene defect follows the pattern of a mendelian pattern of inheritance and is known as Mendelian disorders. Sickle cell anemia is a blood-related disorder in which there is a decrease in healthy red blood cells.

B.

Expert Solution

Explanation of Solution

The sickle cell anemia is an inherited disorder that affects the hemoglobin molecule present in the red blood cell, responsible for carrying the oxygen throughout the body. The people with sickle cell anemia have an abnormal hemoglobin molecule S, which affects the shape of the red blood cell and convert it to a sickle shape.

The mother has sickle cell anemia with genotype Hb^SHb^S, whereas the father may be normal (Hb^AHb^A) or a carrier (Hb^AHb^A) of the trait. If the father is the carrier of the trait, then the chances of the child getting the disorder are 50%, and if the father is normal, then the next generation will be 100% carrier of the disorder.

Answer 13

B.

Summary Introduction

To determine: The probability of their child having the disease or being a carrier of the sickle cell trait.

Introduction: The single gene defect follows the pattern of a mendelian pattern of inheritance and is known as Mendelian disorders. Sickle cell anemia is a blood-related disorder in which there is a decrease in healthy red blood cells.

Answer 14

B.

Expert Solution

Explanation of Solution

The sickle cell anemia is an inherited disorder that affects the hemoglobin molecule present in the red blood cell, responsible for carrying the oxygen throughout the body. The people with sickle cell anemia have an abnormal hemoglobin molecule S, which affects the shape of the red blood cell and convert it to a sickle shape.

The mother has sickle cell anemia with genotype Hb^SHb^S, whereas the father may be normal (Hb^AHb^A) or a carrier (Hb^AHb^A) of the trait. If the father is the carrier of the trait, then the chances of the child getting the disorder are 50%, and if the father is normal, then the next generation will be 100% carrier of the disorder.