Campbell Biology Concepts And Connections - 10th Nasta Edition
Campbell Biology Concepts And Connections - 10th Nasta Edition
10th Edition
ISBN: 9780136646099
Author: Taylor, Simon, Dickey, Hogan, Reece
Publisher: PEARSON
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Chapter 6, Problem 18TYK

For a short time in the 1930s, some physicians prescribed low doses of a compound called dinitrophenol (DNP) to help patients lose weight. This unsafe method was abandoned after some patients died. DNP uncouples the chemiosmotic machinery by making the inner mitochondrial membrane leaky to H+. Explain how this drug could cause profuse sweating, weight loss, and possibly death.

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