Campbell Biology (10th Edition)
10th Edition
ISBN: 9780321775658
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Chapter 56.4, Problem 3CC
MAKE CONNECTIONS → Mutagens are chemical and physical agents that induce mutations in DNA (see Concept 17.5). How does reduced ozone concentration in the atmosphere increase the likelihood of mutations in various organisms?
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E17. Gene mutagenesis is also used to explore the structure and function
of proteins. For example, changes can be made to the coding
sequence of a gene to determine how alterations in the amino acid
sequence affect the function of a protein. Let's suppose that you are
interested in the functional importance of a particular glutamic acid
(an amino acid) within a protein you are studying. By site-directed
mutagenesis, you make mutant proteins in which this glutamic
acid codon has been changed to other codons. You then test the
encoded mutant proteins for functionality. The results are as follows:
Functionality (%)
Normal protein
100
Mutant proteins containing
Тугosine
Phenylalanine
3
Aspartic acid
94
Glycine
From these results, what would you conclude about the functional
significance of this glutamic acid within the protein?
MAKE CONNECTIONS Speculate about whether thesame enzyme could methylate both a histone and a DNAbase. (See Concept 5.4.)
Chapter 56 Solutions
Campbell Biology (10th Edition)
Ch. 56.1 - Explain why it is too narrow to define the...Ch. 56.1 - Identify the four main threats to biodiversity and...Ch. 56.1 - WHAT IF? Imagine two populations of a fish...Ch. 56.2 - How does the reduced genetic diversity of small...Ch. 56.2 - If there were 100 greater prairie chickens in a...Ch. 56.2 - WHAT IF? In 2005, at least ten grizzly bears in...Ch. 56.3 - Prob. 1CCCh. 56.3 - Prob. 2CCCh. 56.3 - Prob. 3CCCh. 56.4 - How can the addition of excess mineral nutrients...
Ch. 56.4 - Prob. 2CCCh. 56.4 - MAKE CONNECTIONS Mutagens are chemical and...Ch. 56.5 - What is meant by the term sustainable development?Ch. 56.5 - Prob. 2CCCh. 56.5 - WHAT IF? Suppose a new fishery is discovered, and...Ch. 56 - Give at least three examples of key ecosystem...Ch. 56 - Why is the minimum viable population size smaller...Ch. 56 - Prob. 56.3CRCh. 56 - Prob. 56.4CRCh. 56 - Prob. 56.5CRCh. 56 - One characteristic that distinguishes a population...Ch. 56 - The main cause of the increase in the amount of...Ch. 56 - Prob. 3TYUCh. 56 - Which of the following is a consequence of...Ch. 56 - Which of the following strategies would most...Ch. 56 - Of the following statements about protected areas...Ch. 56 - Prob. 7TYUCh. 56 - Prob. 8TYUCh. 56 - Prob. 9TYUCh. 56 - WRITE ABOUT A THEME: INTERACTIONS One factor...Ch. 56 - Prob. 11TYU
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- construct! Which of the four constructs (Construct 1-4) below could you use to make your own mouse knockout? For each one you did not choose, explain why you did not choose that construct. Part of DHCR7 gene structure is shown on top row in the schematic. (Antibiotic selection and negative selection genes have been abbreviated.) Gene DHCR7 Intron 1 Exon 2 Intron 2 Exon 3 Exon1 Construct #1 Construct #2 Intron1 Negative Sel. Intron1 |Antibio. Sel. Negative Sel. Intron2 Antibio. Sel Intron 2 Construct #3 Construct #4 Introni Antibio. Sel Negative Sel. Negative Sel. Antibio. Sel. Intron2 Intron1 Intron2arrow_forward. Discuss how mutations may arise in DNA, and the potential consequences for gene function if a point mutation were to occur in (a) the coding region of a gene, and (b) the non-coding regulatory region of a gene.arrow_forwardPrimer Development Pick your favorite gene and develop primers for a target within the gene. Provide the following information: Gene name: Species: Accession number: Primer target: Primer Output: Explain why you selected this primer set.arrow_forward
- Plz asaparrow_forwardWith respect to wobble hypothesis all of the following are correct except: An inosine nucleotide in the mRNA molecule can base-pair with A, C, and U in the tRNA The anticodon shows both standard and non-standard base pairing with the codon at wobble position Guanine can base-pair with uracil An inosine nucleotide in the tRNA molecule can base-pair with A, C and U in the mRNAarrow_forwardusing example what is a degenerate primer? with the aid of diagrams discuss how degenerate primers are used to introduce random mutations in a gene and list some advantages and disadvantages of generating modified protein by this method .arrow_forward
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY