Campbell Biology in Focus (2nd Edition)
Campbell Biology in Focus (2nd Edition)
2nd Edition
ISBN: 9780321962751
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Chapter 5.6, Problem 3CC

WHAT IF? How can a target cell’s response to a single hormone molecule result in a response that affects a million other molecules?

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The binding of small amounts of hormones to target cell receptors triggers an intricate signal cascade. Why is the signal cascade necessary? Why not just have a simple molecularmechanism between the hormone and cellular effect?
Yellow: Did not have answers from anyone but confident based on notes Question 1: Insulin can have pleiotropic (wide ranging) effects in cells because...? 1. The insulin receptor phosphorylates with a family of substrates inside the cell 2. There are over 20 versions of the insulin receptor expressed in vertebrates 3. The insulin receptor heterodimers with the GH and PRL receptors 4. MRAP (membrane associated receptor proteins) couple the insulin receptor to different effector pathways Question 2: Cholecystokinin (CCK) is accurately described by which of the following statements? 1. It is not a member of the peptide hormone superfamily 2. It binds to a 1-TMS receptor that signals through guanylate cyclase 3. It is sulphated on tyrosine residues for full activity 4. It is proteolytically released from POMC by gut cells Question 3: Insulin... 1. Is released from the pancreas in vertebrates and invertebrates 2. Is released from the vertebrate pancreas in response to hyperglycemia 3. Is…

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Campbell Biology in Focus (2nd Edition)

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