Pharmacology and the Nursing Process
7th Edition
ISBN: 9780323087896
Author: Linda Lane Lilley
Publisher: Elsevier Health Sciences
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Question
Chapter 54, Problem 1O
Summary Introduction
To discuss:
The importance of vitamin B12, folic acid, and iron in the formation of blood cells.
Concept introduction:
The development and formation of blood cells in the bone marrow are termed as hematopoiesis. This process includes the production of leukocytes (white blood cells), erythrocytes (red blood cells), and thrombocytes. These blood cells are produced in the bone marrow or myeloid tissues. Iron, folic acid, and vitamin B12 play an important role in the maturation of the red blood cells.
Expert Solution & Answer
Explanation of Solution
The red blood cells are manufactured in the bone marrow and are released into circulation in the form of immature red blood cells. Iron is an important component for the production of blood cells and is called hemoglobin. Hemoglobin carries oxygen in the blood to transfer oxygen to all parts of the body from the lungs. Iron helps in the cytoplasmic maturation of the red blood cells.
Folic acid and vitamin B12 help in the nuclear maturation of the red blood cells. Folic acid is converted into tetrahydrofolic acid in the body and is used in the red blood cell formation (erythropoiesis) for the synthesis of
Deficiency of iron, folic acid, and vitamin B12 leads to various types of anemia.
Conclusion
The maturation of the nucleus and cytoplasm of the red blood cells during erythropoiesis is carried out by the components such as iron, folic acid, and vitamin B12. Thus, these components are very essential for the normal functions of the body and their deficiency leads to immature formation of blood cells.
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