The four factors (natality, mortality, immigration, and emigration) that produce changes in population size and solve simple problems involving these changes. Introduction: Population change is caused by many factors. Any of these factors can lead to a change in population to some or great extent. Study of these factors and their effects on population is very important to understand a population at a given time instance. Some of these factors are: natality, mortality, immigration, and emigration.

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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for? 3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2

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Chapter 53.2, Problem 2LO

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To explain: The four factors (natality, mortality, immigration, and emigration) that produce changes in population size and solve simple problems involving these changes.

Introduction: Population change is caused by many factors. Any of these factors can lead to a change in population to some or great extent. Study of these factors and their effects on population is very important to understand a population at a given time instance. Some of these factors are: natality, mortality, immigration, and emigration.

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