Chapter 52, Problem 1S

Summary Introduction

To determine:

The changes that would be expected when there is mutation in the SRY gene such that a male embryo could not produce functional protein.

Introduction:

In humans, the sex determination system relies on the X and Y chromosome. The egg of female contributes X chromosome, while the sperm of the male contribute to either Y chromosome or X chromosome. These combinations will result in male (XY) or female (XX) offspring respectively. SRY (sex-determining region Y) is present on the Y chromosome of males, which is responsible for the development of male in humans.