EBK LIFE: THE SCIENCE OF BIOLOGY
EBK LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 8220103935432
Author: Sadava
Publisher: MAC HIGHER
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Chapter 50.4, Problem 4R
Summary Introduction

To review:

The results, which led to the conclusion that nutritional state alters the body mass and not just the ability to produce satiety or hunger.

Introduction:

Many areas of brain are involved in controlling the desire to eat and feeling of satiety or feeling full. The hypothalamus is an area of the brain, which has many small nuclei with a variety of functions.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
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