Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 5, Problem 33ESP
The gene controlling the Xg blood group alleles (Xg+ and Xg−) and the gene controlling a newly described form of inherited recessive muscle weakness called episodic muscle weakness (EMWX) (Ryan et al., 1999) are closely linked on the X chromosome in humans at position Xp22.3 (the tip of the short arm). A male with EMWX who is Xg− marries a woman who is Xg+, and they have eight daughters and one son, all of whom are normal for muscle function, the male being Xg+ and all the daughters being heterozygous at both the EMWX and Xg loci. Following is a table that lists three of the daughters with the
- (a) Create a pedigree that represents all data stated above and in the following table.
- (b) For each of the offspring, indicate whether or not a crossover was required to produce the phenotypes that are given.
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In Drosophila the genes forked bristles (f and f+) and vermilion eyes (v and v+) are ~24 m.u. apart on the X chromosome.
From a cross of f v / f+ v+ females with f v / y males, what % of the progeny do you expect to have the f+ v+ phenotypes? (Don’t let the X chromosome throw you off – this question is essentially asking what % of the female’s gametes will be f+ v+).
+ ec +/Y
+ + w/Y
y ec +/Y
+ ec +/y ec w
++ w/y ec w
у ес +у ес и
Determine the order in which the three loci y, ec, and w
Occur on the chromosome and prepare a linkage map.
7.22 A cross involving X-linked genes was made between
yellow, bar, vermilion female fies and wild males, and the F1
females were crossed with y B v males. The following
phenotypes were obtained when 1000 progeny were exam-
ined:
Dra
ord
ma
the
7.2
546
244
160
50
+ + +
+ Bv
y Bv
y+ +
y+v
y B+
and
an
and
and
and
+B +
re
+ + v
ge
Determine the order in which the three loci occur on the
chromosome and prepare a linkage map.
7.23 Female Drosophila heterozygous for ebony (e"le),
scarlet (st*/st), and spineless (ss*/ss) were testcrossed, and
the following progeny were obtained:
PROGENCY PHENOTYPES
NUMBER
ir
Wild type
Ebony
Ebony, scarlet
Ebony, spineless
Ebony, scarlet, spineless
Scarlet
67
8.
68
347
78
368
Scarlet, spineless
Spineless
(a) Are these genes linked? Justify your answer. (b) Write the
genes given on a…
In humans, chromosome 16 sometimes has a heavily stained area near the
centromere. This feature can be seen in a microscope, but otherwise has no
effect on the phenotype of the person carrying it. When such a “blob" exists on
a given copy of chromosome 16, it is a constant feature of that chromosome
and is inherited.
A couple conceived a child, but the fetus had multiple abnormalities and was
miscarried. e.g., The fetus had three copies of chromosome 16, where 2 of the
3 copies of chromosome 16 had large blobs. Both of the mother's copies of
chromosome 16 lacked blobs, but the father was heterozygous for blobs. The
fetus was formed from a fertilization event that included a gamete produced
by the
in which nondisjunction occurred during the
meiotic
division.
Select an answer and submit. For keyboard navigation, use the up/down arrow keys to
select an answer.
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mother; first.
mother; second.
father; first.
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Your answer
d
father; second.
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Chapter 5 Solutions
Concepts of Genetics (12th Edition)
Ch. 5 - In a family with one autistic child the risk for...Ch. 5 - Given that the prenatal test can provide only a...Ch. 5 - Consider two hypothetical recessive autosomal...Ch. 5 - With two pairs of genes involved (P/p and Z/z), a...Ch. 5 - In Drosophila, a heterozygous female for the...Ch. 5 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 5 - Review the Chapter Concepts list on page 94. Most...Ch. 5 - Describe the cytological observation that suggests...Ch. 5 - Why does more crossing over occur between two...Ch. 5 - Explain why a 50 percent recovery of...
Ch. 5 - Why are double-crossover events expected less...Ch. 5 - What is the proposed basis for positive...Ch. 5 - What two essential criteria must be met in order...Ch. 5 - The genes dumpy (dp), clot (cl), and apterous (ap)...Ch. 5 - Colored aleurone in the kernels of com is due to...Ch. 5 - In the cross shown here, involving two linked...Ch. 5 - In a series of two-point mapping crosses involving...Ch. 5 - Two different female Drosophila were isolated,...Ch. 5 - In Drosophila, a cross was made between femalesall...Ch. 5 - Another cross in Drosophila involved the...Ch. 5 - In Drosophila, Dichaete (D) is a mutation on...Ch. 5 - Drosophila females homozygous for the third...Ch. 5 - In Drosophila, two mutations, Stubble (Sb) and...Ch. 5 - If the cross described in Problem 18 were made,...Ch. 5 - Are mitotic recombinations and sister chromatid...Ch. 5 - What possible conclusions can be drawn from the...Ch. 5 - An organism of the genotype AaBbCc was testcrossed...Ch. 5 - Based on our discussion of the potential...Ch. 5 - Traditional gene mapping has been applied...Ch. 5 - DNA markers have greatly enhanced the mapping of...Ch. 5 - In a certain plant, fruit is either red or yellow,...Ch. 5 - Two plants in a cross were each heterozygous for...Ch. 5 - A number of humanmouse somatic cell hybrid clones...Ch. 5 - A female of genotype produces 100 meiotic tetrads....Ch. 5 - In laboratory class, a genetics student was...Ch. 5 - Drosophila melanogaster has one pair of sex...Ch. 5 - In Drosophila, a female fly is heterozygous for...Ch. 5 - The gene controlling the Xg blood group alleles...Ch. 5 - Prob. 34ESP
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