BIOLOGY-TEXT
5th Edition
ISBN: 9781260169621
Author: BROOKER
Publisher: MCG
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Chapter 5, Problem 1COQ
Summary Introduction
To determine: The reason for the proteins inside the plasma membrane is the target of various medicines.
Introduction: Various types of important roles are performed by the proteins of the plasma membrane. These proteins are very important for the normal
Summary Introduction
To determine: The way by which it can be experimentally proved that a specific membrane protein act as the target of a particular drug.
Introduction: Various types of important roles are performed by the proteins of the plasma membrane. These proteins are very important for the normal metabolic functions of the living organisms.
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Proteins in the plasma membrane are often the target of medicines.Discuss why you think this is the case. How would you determineexperimentally that a specific membrane protein was the target of adrug?
You are working on a team that is designing a new drug. For this drug to work, it must enter the cytoplasm of specific
target cells.
Which of the following would be a factor that determines whether the molecule selectively enters the target cells?
O the phospholipid composition of the target cells' plasma membrane
O the nonpolar, hydrophobic nature of the drug molecule
the similarity of the drug molecule to other molecules that are transported into the target cells
the concentration of the drug molecule that is transported in the blood
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Request Answer
Which of the following statements are correct about how the complex biological matrix of the cell may affect protein folding, stability and function (select all that appy)?
A.
ATP tends to "bounce" along the surfaces of many proteins without forming a stable complex
B.
Proteins make up approximately 30% of the total volume of the cytoplasm in a typical cell
C.
Compettition between drug molecules and metabolites in the cytoplasm may cause unexpected drug side effects not seen with individual proteins in solution.
D.
Large protein complexes move faster through the cytoplasm than small metabolites.
E.
Complex intercations between proteins in the cell may significantly destabilize a protein compared to the isolated protein in water
Chapter 5 Solutions
BIOLOGY-TEXT
Ch. 5.1 - Core Skill: Modeling The goal of this modeling...Ch. 5.2 - Prob. 1CSCh. 5.3 - Prob. 1CCCh. 5.3 - Prob. 2CCCh. 5.4 - Prob. 1CSCh. 5.4 - Prob. 2CSCh. 5.4 - Lets suppose the inside of a cell has a solute...Ch. 5.5 - What is the purpose of gating?Ch. 5.5 - Prob. 1EQCh. 5.5 - Prob. 2EQ
Ch. 5.5 - Prob. 3EQCh. 5.6 - What is the function of the protein coat?Ch. 5 - Prob. 1TYCh. 5 - Which of the following events can never be...Ch. 5 - Lets suppose an insect, which doesnt maintain a...Ch. 5 - Prob. 4TYCh. 5 - Prob. 5TYCh. 5 - Prob. 6TYCh. 5 - Prob. 7TYCh. 5 - Prob. 8TYCh. 5 - Prob. 9TYCh. 5 - Large particles or large volumes of fluid can be...Ch. 5 - With your textbook closed, draw and describe the...Ch. 5 - Prob. 2CQCh. 5 - Prob. 3CQCh. 5 - Prob. 1COQCh. 5 - With regard to bringing solutes into the cell...
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- Moat drug act by altering the various body control systems.Name the binding site located on the surface of the cell to which drug binds to show its action with example of such drugs. Mention 2 drugs that act by inhibiting transport.arrow_forward8) Indicate which of the five major types of membrane protein (adhesion, enzymatic, recognition, receptor, and transport) is most likely to be involved in each of the situations described below: a) An oncologist wants to study the cells from a certain tumour that has been surgically removed from a patient. However, she must first treat the tumour with a solution affects a membrane protein on the tumour cells. Because of the effect of the solution on the membrane protein, the tumour tissue falls apart into individual cells. Type of membrane protein: b) Farmer Jebediah wakes up in the morning and makes himself an extra-strong coffee. The caffeine in the coffee attaches to a protein in the plasma membrane of his neurons, inducing a signal transduction cascade and causing Farmer Jebediah to be more alert Type of membrane protein:arrow_forwardFill in the blanks please.arrow_forward
- Cell adhesion molecules (CAMs) can form cis and trans interactions with other CAM molecules. True or Falsearrow_forwardSome antimicrobial drugs used to treat bacterial infections disrupt the process of protein synthesis. What could these drugs target? Why would this ultimately lead to cell death?arrow_forwardOsmosis Practice Activity Osmosis is the diffusion of water from an area of high concentration to an area of low concentration. Only water moves in osmosis! The diagrams below show the concentration of water and salt inside the cell and the concentration of water and salt surrounding the cell. Complete the sentences below by comparing the concentration of the water inside the cell and the concentration outside the cell. 1. a. Water will flow the cell, out of the cell, in both directions). (into 5% NaCl 95% H20 95% NaCI 5% H20 b. The cell will (shrink, burst, stay the same). a. Water will flow (into the cell. 2. 5% NaCl out of the cell, in both directions). 5% NaCl 95% H20 95% H20 b. The cell will (shrink, burst, stay the same).arrow_forward
- There are 4 basic tissues in the human body. For each of the following organs/structures describe the location and function of at least three basic tissues found in them. Heart and stomach You have received GHS 1 million as a scientist to develop a vaccine for corona virus. You have been able to develop the vaccine but now the challenge is how the vaccine will enter the cells of the body when you inject it. From your knowledge of the structure of the cell membrane give and explain 2 features you can exploit in order for the vaccine to go across the cell membrane into the cell.arrow_forwardAll are protiens of cell membrane that are involved in flow of nerve impulse except 1-channel proteins 2-carrier protiens 3-peripheral protiens 4-integral protiens Also give explanationarrow_forwardGap junctions and tunneling nanotubes are two distinct types of direct intracellular communication. In comparing and contrasting gap junctions and tunneling nanotubes, which of the following statements is true? gap junctions provide a portal for small molecules, proteins and small organelles to move from cell to cell, tunneling nanotubes only permit small molecules to pass between cells typically, there are only two gap junctions that exist between adjacent cells that are communicating via this mechanism; on the other hand, there are many tunneling nanotubes between communicating cells both gap junctions and tunneling nanotubes can pass small molecules between cells none of the above is truearrow_forward
- Phagocytosis of a bacterial cell by a macrophage, involves extensive remodeling of the actin microfilaments in the cell cortex to produce extensions of the plasma membrane and formation the phagocytic cup. Based on your knowledge of microfilament assembly/disassembly and related cell membrane deformation, explain the underlying processes that would be involved in formation of the phagocytic cup.arrow_forwardTo improve the efficiency of axonal transport, bundles of similar proteins are packaged and transported together instead of individually. This is described by the: Transport Efficiency Hypothesis Microtubule Hypothesis Theory of Relativity Structural Hypothesisarrow_forwardexplain elaborately about the plasma membrane acts as a selective gatekeeper, the importance of it and function of being a gatekeeper of the cells (300 to 500 words)arrow_forward
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