BIOLOGY-TEXT
BIOLOGY-TEXT
5th Edition
ISBN: 9781260169621
Author: BROOKER
Publisher: MCG
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Chapter 5, Problem 1COQ
Summary Introduction

To determine: The reason for the proteins inside the plasma membrane is the target of various medicines.

Introduction: Various types of important roles are performed by the proteins of the plasma membrane. These proteins are very important for the normal metabolic functions of the living organisms.

Summary Introduction

To determine: The way by which it can be experimentally proved that a specific membrane protein act as the target of a particular drug.

Introduction: Various types of important roles are performed by the proteins of the plasma membrane. These proteins are very important for the normal metabolic functions of the living organisms.

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Proteins in the plasma membrane are often the target of medicines.Discuss why you think this is the case. How would you determineexperimentally that a specific membrane protein was the target of adrug?
You are working on a team that is designing a new drug. For this drug to work, it must enter the cytoplasm of specific target cells. Which of the following would be a factor that determines whether the molecule selectively enters the target cells? O the phospholipid composition of the target cells' plasma membrane O the nonpolar, hydrophobic nature of the drug molecule the similarity of the drug molecule to other molecules that are transported into the target cells the concentration of the drug molecule that is transported in the blood Submit Request Answer
Which of the following statements are correct about how the complex biological matrix of the cell may affect protein folding, stability and function (select all that appy)?   A. ATP tends to "bounce" along the surfaces of many proteins without forming a stable complex   B. Proteins make up approximately 30% of the total volume of the cytoplasm in a typical cell   C. Compettition between drug molecules and metabolites in the cytoplasm may cause unexpected drug side effects not seen with individual proteins in solution.   D. Large protein complexes move faster through the cytoplasm than small metabolites.   E. Complex intercations between proteins in the cell may significantly destabilize a protein compared to the isolated protein in water
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