EBK BIOLOGY
EBK BIOLOGY
10th Edition
ISBN: 8220100474729
Author: Martin
Publisher: Cengage Learning US
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Chapter 47, Problem 12TYU
Summary Introduction

To design: An experiment to test the hypothesis that B vitamin pyridoxine is an essential nutrient in mice.

Introduction: Essential nutrients are the nutrients that cannot be synthesized by one’s own body but are required to carry out the normal physiological functions and must be provided through diet. There are six essential nutrients: carbohydrates, fats, protein, vitamins, minerals, and water.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
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