The mechanism of antibodies that attack the glycoproteins in the lamina Lucida and their attachment to the hemi desmosomes that can cause blisters. Introduction: An infectious disease is the one that is caused by pathogenic microbes. These microbes can be bacteria, parasites , viruses or fungi . They are usually harmless but in some conditions that can be lethal. Infectious diseases can be transmitted from one person (infected) to another person (non-infected).

Question

Want to see more full solutions like this?

Answer 1

Question

Definition Definition Organism that lives in the body of another organism and obtains food at the expense of the host. A parasite can directly or indirect harm the host. There are two kinds of parasites: internal and external. An internal parasite lives inside another organism and is known as an endoparasite. An external parasite lives on the body surface of the host and is known as an ectoparasite. Protozoa and helminths are examples of major human parasites.

Chapter 45, Problem 1RE

Summary Introduction

To determine: The mechanism of antibodies that attack the glycoproteins in the lamina Lucida and their attachment to the hemi desmosomes that can cause blisters.

Introduction: An infectious disease is the one that is caused by pathogenic microbes. These microbes can be bacteria, parasites, viruses or fungi. They are usually harmless but in some conditions that can be lethal. Infectious diseases can be transmitted from one person (infected) to another person (non-infected).

Expert Solution & Answer

Explanation of Solution

Bullous pemphigoid is the most common form of the autoimmune disease that causes the formation of blisters which is induced by the autoantibodies that form against the type XVII collagen. It is an autoimmune subepithelial blistering disease that occurs most frequently in older adults and is characterized by presence of cutaneous bullae and erosive mucosal lesions.

The autoantibodies against the hemidesmosome antigen of type XVII collagen is supposed to induce the inflammatory processes that result in dermal-epidermal separation (BP180). The COL17 is a type II transmembrane protein that spans the lamina Lucida. Most patients have autoantibodies binding to an immunodominant region of BP180, which is located extracellularly close to transmembrane domain of the protein.

Patients’ autoantibodies to BP180 induce dermal-epidermal separation in cryosections of human skin when co-incubated with leukocytes. The loss of cell-matrix adhesion is mediated by proteinases released by granulocytes.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Students have asked these similar questions

Skip to main content close Homework Help is Here – Start Your Trial Now! arrow_forward search SEARCH ASK Human Anatomy & Physiology (11th Edition)BUY Human Anatomy & Physiology (11th Edition) 11th Edition ISBN: 9780134580999 Author: Elaine N. Marieb, Katja N. Hoehn Publisher: PEARSON 1 The Human Body: An Orientation expand_moreChapter 1 : The Human Body: An Orientation Chapter Questions expand_moreSection: Chapter Questions Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,... format_list_bulletedProblem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,... See similar textbooks Bartleby Related Questions Icon Related questions Bartleby Expand Icon bartleby Concept explainers bartleby Question Draw a replication bubble with two replication forks.blue lines are DNA single strands and red lines are RNA single strands.indicate all 3' and 5’ ends on all DNA single…

Provide an answer

Question 4 1 pts Which of the following would be most helpful for demonstrating alternative splicing for a new organism? ○ its proteome and its transcriptome only its transcriptome only its genome its proteome and its genome

Answer 2

Question

Definition Definition Organism that lives in the body of another organism and obtains food at the expense of the host. A parasite can directly or indirect harm the host. There are two kinds of parasites: internal and external. An internal parasite lives inside another organism and is known as an endoparasite. An external parasite lives on the body surface of the host and is known as an ectoparasite. Protozoa and helminths are examples of major human parasites.

Chapter 45, Problem 1RE

Summary Introduction

To determine: The mechanism of antibodies that attack the glycoproteins in the lamina Lucida and their attachment to the hemi desmosomes that can cause blisters.

Introduction: An infectious disease is the one that is caused by pathogenic microbes. These microbes can be bacteria, parasites, viruses or fungi. They are usually harmless but in some conditions that can be lethal. Infectious diseases can be transmitted from one person (infected) to another person (non-infected).

Expert Solution & Answer

Explanation of Solution

Bullous pemphigoid is the most common form of the autoimmune disease that causes the formation of blisters which is induced by the autoantibodies that form against the type XVII collagen. It is an autoimmune subepithelial blistering disease that occurs most frequently in older adults and is characterized by presence of cutaneous bullae and erosive mucosal lesions.

The autoantibodies against the hemidesmosome antigen of type XVII collagen is supposed to induce the inflammatory processes that result in dermal-epidermal separation (BP180). The COL17 is a type II transmembrane protein that spans the lamina Lucida. Most patients have autoantibodies binding to an immunodominant region of BP180, which is located extracellularly close to transmembrane domain of the protein.

Patients’ autoantibodies to BP180 induce dermal-epidermal separation in cryosections of human skin when co-incubated with leukocytes. The loss of cell-matrix adhesion is mediated by proteinases released by granulocytes.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Question

Definition Definition Organism that lives in the body of another organism and obtains food at the expense of the host. A parasite can directly or indirect harm the host. There are two kinds of parasites: internal and external. An internal parasite lives inside another organism and is known as an endoparasite. An external parasite lives on the body surface of the host and is known as an ectoparasite. Protozoa and helminths are examples of major human parasites.

Chapter 45, Problem 1RE

Summary Introduction

To determine: The mechanism of antibodies that attack the glycoproteins in the lamina Lucida and their attachment to the hemi desmosomes that can cause blisters.

Introduction: An infectious disease is the one that is caused by pathogenic microbes. These microbes can be bacteria, parasites, viruses or fungi. They are usually harmless but in some conditions that can be lethal. Infectious diseases can be transmitted from one person (infected) to another person (non-infected).

Expert Solution & Answer

Explanation of Solution

Bullous pemphigoid is the most common form of the autoimmune disease that causes the formation of blisters which is induced by the autoantibodies that form against the type XVII collagen. It is an autoimmune subepithelial blistering disease that occurs most frequently in older adults and is characterized by presence of cutaneous bullae and erosive mucosal lesions.

The autoantibodies against the hemidesmosome antigen of type XVII collagen is supposed to induce the inflammatory processes that result in dermal-epidermal separation (BP180). The COL17 is a type II transmembrane protein that spans the lamina Lucida. Most patients have autoantibodies binding to an immunodominant region of BP180, which is located extracellularly close to transmembrane domain of the protein.

Patients’ autoantibodies to BP180 induce dermal-epidermal separation in cryosections of human skin when co-incubated with leukocytes. The loss of cell-matrix adhesion is mediated by proteinases released by granulocytes.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Question

Definition Definition Organism that lives in the body of another organism and obtains food at the expense of the host. A parasite can directly or indirect harm the host. There are two kinds of parasites: internal and external. An internal parasite lives inside another organism and is known as an endoparasite. An external parasite lives on the body surface of the host and is known as an ectoparasite. Protozoa and helminths are examples of major human parasites.

Chapter 45, Problem 1RE

Summary Introduction

To determine: The mechanism of antibodies that attack the glycoproteins in the lamina Lucida and their attachment to the hemi desmosomes that can cause blisters.

Introduction: An infectious disease is the one that is caused by pathogenic microbes. These microbes can be bacteria, parasites, viruses or fungi. They are usually harmless but in some conditions that can be lethal. Infectious diseases can be transmitted from one person (infected) to another person (non-infected).

Expert Solution & Answer

Explanation of Solution

Bullous pemphigoid is the most common form of the autoimmune disease that causes the formation of blisters which is induced by the autoantibodies that form against the type XVII collagen. It is an autoimmune subepithelial blistering disease that occurs most frequently in older adults and is characterized by presence of cutaneous bullae and erosive mucosal lesions.

The autoantibodies against the hemidesmosome antigen of type XVII collagen is supposed to induce the inflammatory processes that result in dermal-epidermal separation (BP180). The COL17 is a type II transmembrane protein that spans the lamina Lucida. Most patients have autoantibodies binding to an immunodominant region of BP180, which is located extracellularly close to transmembrane domain of the protein.

Patients’ autoantibodies to BP180 induce dermal-epidermal separation in cryosections of human skin when co-incubated with leukocytes. The loss of cell-matrix adhesion is mediated by proteinases released by granulocytes.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Chapter 45, Problem 1RE

Summary Introduction

To determine: The mechanism of antibodies that attack the glycoproteins in the lamina Lucida and their attachment to the hemi desmosomes that can cause blisters.

Introduction: An infectious disease is the one that is caused by pathogenic microbes. These microbes can be bacteria, parasites, viruses or fungi. They are usually harmless but in some conditions that can be lethal. Infectious diseases can be transmitted from one person (infected) to another person (non-infected).

Expert Solution & Answer

Explanation of Solution

Bullous pemphigoid is the most common form of the autoimmune disease that causes the formation of blisters which is induced by the autoantibodies that form against the type XVII collagen. It is an autoimmune subepithelial blistering disease that occurs most frequently in older adults and is characterized by presence of cutaneous bullae and erosive mucosal lesions.

The autoantibodies against the hemidesmosome antigen of type XVII collagen is supposed to induce the inflammatory processes that result in dermal-epidermal separation (BP180). The COL17 is a type II transmembrane protein that spans the lamina Lucida. Most patients have autoantibodies binding to an immunodominant region of BP180, which is located extracellularly close to transmembrane domain of the protein.

Patients’ autoantibodies to BP180 induce dermal-epidermal separation in cryosections of human skin when co-incubated with leukocytes. The loss of cell-matrix adhesion is mediated by proteinases released by granulocytes.

Answer 6

Chapter 45, Problem 1RE

Summary Introduction

To determine: The mechanism of antibodies that attack the glycoproteins in the lamina Lucida and their attachment to the hemi desmosomes that can cause blisters.

Introduction: An infectious disease is the one that is caused by pathogenic microbes. These microbes can be bacteria, parasites, viruses or fungi. They are usually harmless but in some conditions that can be lethal. Infectious diseases can be transmitted from one person (infected) to another person (non-infected).

Expert Solution & Answer

Explanation of Solution

Bullous pemphigoid is the most common form of the autoimmune disease that causes the formation of blisters which is induced by the autoantibodies that form against the type XVII collagen. It is an autoimmune subepithelial blistering disease that occurs most frequently in older adults and is characterized by presence of cutaneous bullae and erosive mucosal lesions.

The autoantibodies against the hemidesmosome antigen of type XVII collagen is supposed to induce the inflammatory processes that result in dermal-epidermal separation (BP180). The COL17 is a type II transmembrane protein that spans the lamina Lucida. Most patients have autoantibodies binding to an immunodominant region of BP180, which is located extracellularly close to transmembrane domain of the protein.

Patients’ autoantibodies to BP180 induce dermal-epidermal separation in cryosections of human skin when co-incubated with leukocytes. The loss of cell-matrix adhesion is mediated by proteinases released by granulocytes.

Answer 7

Chapter 45, Problem 1RE

Summary Introduction

To determine: The mechanism of antibodies that attack the glycoproteins in the lamina Lucida and their attachment to the hemi desmosomes that can cause blisters.

Introduction: An infectious disease is the one that is caused by pathogenic microbes. These microbes can be bacteria, parasites, viruses or fungi. They are usually harmless but in some conditions that can be lethal. Infectious diseases can be transmitted from one person (infected) to another person (non-infected).

Answer 8

Expert Solution & Answer

Explanation of Solution

Bullous pemphigoid is the most common form of the autoimmune disease that causes the formation of blisters which is induced by the autoantibodies that form against the type XVII collagen. It is an autoimmune subepithelial blistering disease that occurs most frequently in older adults and is characterized by presence of cutaneous bullae and erosive mucosal lesions.

The autoantibodies against the hemidesmosome antigen of type XVII collagen is supposed to induce the inflammatory processes that result in dermal-epidermal separation (BP180). The COL17 is a type II transmembrane protein that spans the lamina Lucida. Most patients have autoantibodies binding to an immunodominant region of BP180, which is located extracellularly close to transmembrane domain of the protein.

Patients’ autoantibodies to BP180 induce dermal-epidermal separation in cryosections of human skin when co-incubated with leukocytes. The loss of cell-matrix adhesion is mediated by proteinases released by granulocytes.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Ch. 45 - Prob. 1RE Ch. 45 - Prob. 2RE

Explanation of Solution

Want to see more full solutions like this?

Chapter 45 Solutions