Campbell Biology (11th Edition)
11th Edition
ISBN: 9780134093413
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Chapter 43, Problem 5TYU
Summary Introduction
Introduction: The term “MHC” denotes “Major Histocompatibility Complex” molecule. This molecule is the host protein that presents the “antigen fragment” on the surface of the cell. It is essential for “T cells” to make out the foreign antigen. In the same manner, the “MHC molecules” identify the cells from another person as foreign and attack them. This is called immune rejection. These MHC molecules are identical between identical twins, so there will not be immune rejection if an organ is transplanted between identical twins.
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(66)A laboratory animal is scheduled to be immunized by receiving weekly injections of antigen X. Analysis of serum drawn 2 days after the last immunization would show antibodies to antigen X to be primarily of which of the following classes?
(A) IgA
(B) IgD
(C) IgE
(D)IgG
(E)IgM
Human immune system
a) Pathogen-associated molecular patterns are conserved molecular structures produced by microorganisms, but not by host cells.
b) A virus-infected host cell that displays a viral antigen via MHC class I molecules may become a target of cytotoxic T cells.
c) Secreted MHC Class I proteins present in blood plasma can function as opsonins.
d) Both (a) and (b) are correct and (c) is incorrect
e) Statements (a), (b) and (c) are all correct
Immunosuppression is a lowering of the responsiveness ofthe immune system to materials it recognizes as foreign and isproduced by _________and_________ .(a) antibodies and foreign antigens(b) NK cells and allergen desensitizers(c) radiation and cytotoxic drugs(d) hypersensitivity and transplant rejection(e) a and d
Chapter 43 Solutions
Campbell Biology (11th Edition)
Ch. 43.1 - Pus is both a sign of infection and an indicator...Ch. 43.1 - MAKE CONNECTIONS How do the molecules that...Ch. 43.1 - Prob. 3CCCh. 43.2 - Prob. 1CCCh. 43.2 - Prob. 2CCCh. 43.2 - WHAT IF? If both copies of a light-chain gene and...Ch. 43.3 - Prob. 1CCCh. 43.3 - Treatment of antibodies with a particular protease...Ch. 43.3 - Prob. 3CCCh. 43.4 - Prob. 1CC
Ch. 43.4 - Prob. 2CCCh. 43.4 - WHAT IF? How would a macrophage deficiency likely...Ch. 43 - In what ways does innate immunity protect the...Ch. 43 - Why is the adaptive immune response to an initial...Ch. 43 - Is immunological memory after a natural infection...Ch. 43 - Prob. 43.4CRCh. 43 - Prob. 1TYUCh. 43 - An epitope associates with which part of an...Ch. 43 - Prob. 3TYUCh. 43 - Level 2: Application/Analysis 4. Which of the...Ch. 43 - Prob. 5TYUCh. 43 - Prob. 6TYUCh. 43 - Prob. 7TYUCh. 43 - Prob. 8TYUCh. 43 - MAKE CONNECTIONS Contrast clonal selection with...Ch. 43 - EVOLUTION CONNECTION Describe one invertebrate...Ch. 43 - Prob. 11TYUCh. 43 - Prob. 12TYUCh. 43 - SYNTHESIZE YOUR KNOWLEDGE This photo shows a child...
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- Tuberculosis is a chronic respiratory condition caused by Mycobacterium tuberculosis, a high contagious bacterium. People with tuberculosis will often have a persistent (sometimes bloody) cough, fatigue, weight loss, and fever. M. tuberculosis produces a protein we will call “X”. A new test for tuberculosis checks for X antibodies in a person’s blood. If the antibodies are present, the result is “positive.” Why would X antibodies be present in someone’s blood? What specific kind of cells would produce them?arrow_forwardThe major histocompatibility complex (MHC) (a) consists of Y-shaped molecules (b) encodes certain antibodies (c) encodes Toll-like receptors (d) inhibits complement release from macrophages (e) encodes a group ofcell-surface proteins.arrow_forward(74) A rare from of immunologic syndrome is assciated with recurrent skin lesions, eosinophilia, and increased serum concentrations of IgE. In patients with this syndrome , which of the following cytokines is most likely to be increased? (A) Interleukin-1 Beta( Il-1B) (B) Interleukin-2 ( IL-2) (C) Interleukin-4 (IL-4) (D) Interleukin-6 (IL-60 (E) Tumor Necrosis Factor alphaarrow_forward
- These cells synthesize and secrete which of the following molecules: Choose one from the following: (A) perforin and granzymes (B) serotonin (C) immunoglobulin M (D) interleukin-2 (E) interferonarrow_forward1. (a) (b) (c) (d) (e) (f) (g) (h) Provide the word that best fits the definition for each part below. A protein on the surface of macrophages and other immune cells that recognizes and binds the constant regions of antibodies in antibody-antigen complexes. The portion of an antigen that is recognized by a particular antibody. An antibody that is produced by a hybridoma, a hybrid between a normal B cell and a B cell tumor. A pharmaceutical product that is produced from living organisms or contains components of living organisms. Description of a monoclonal antibody that has been engineered to have the original murine variable regions of the heavy and light chains coupled with human constant regions of the heavy and light chains. A generic form of a biologic drug. It is not identical in structure but identical in function, side effects, and toxicity. A new cancer therapy in which the tail end of an anti-cancer antibody is replaced by a T cell. Binding of the antibody to the tumor can…arrow_forwardVaccination increases the number of(A) different receptors that recognize a pathogen.(B) lymphocytes with receptors that can bind to the pathogen.(C) epitopes that the immune system can recognize.(D) MHC molecules that can present an antigenarrow_forward
- The cell marked with the blue dot synthesizes and secretes which of the following: Choose one from the following: (A) serotonin (B) immunoglobulin A (C) interleukin-1 (D) perforins and granzymes (E) interleukin-2arrow_forwardAntibodies against a specific antigen can be injected into a person to provide passive immunity. For which reason is this NOT as effective as the process of vaccination with that antigen? Select one: a. Injection of antibodies may cause allergic reactions, while vaccination never causes allergic reactions. b. Injection of antibodies does not provide long-lasting immunity, and vaccination with antigens triggers a clonal selection of B cells and cytotoxic T cells. c. Vaccination with antigens triggers a clonal selection of B cells and cytotoxic T cells. d. Injection of antibodies does not provide long-lasting immunity. e. Injection of antibodies does not provide long-lasting immunity and may cause allergic reactions, while vaccination never causes allergic reactions.arrow_forwardThe human immune system includes a number of specialized cells. Suggest the activity of the macrophage based on your understanding of cell processes. The macrophage • a) produces large antibody proteins. 9 • b) uses pinocytosis to drink solutes. . 12 • c) engulfs and digests bacteria and other pathogens 15 d) has specific receptor proteins that allow the capture of antigens.arrow_forward
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