Concept explainers
Introduction:
Antigens are the substances which are specifically bounded by antibodies. It is a structural molecule that binds specifically to an antibody only in the form of a native antigen. It evokes an immune response either alone or forming a complex with larger molecules and that is capable of binding with a product of the immune response.
Answer to Problem 1PL
Correct answer:
The correct answer is option (a) on the red blood cell membranes.
Explanation of Solution
Explanation/justification for the correct answer:
Option (a) on the red blood cell membranes. The blood typing involves the identifying of protein substances called antigens, present on the outer surface of the red blood cell membranes. These include the antigens of the ABO group and those of the Rh group. The ABO blood group antigens are attached to the oligosaccharide chains that project over the surface of red blood cells. These chains are attached to proteins and lipids that lie over the surface of the red blood cell membrane. So, the correct answer is option (b).
Explanation for incorrect answer:
Option (b) within the red blood cell nucleus. The ABO blood group antigens are attached to the oligosaccharide chains that project over the surface of red blood cells and not within the nucleus. Also, the red blood cells are devoid of nucleus. So, this is an incorrect option.
Option (c) within the red blood cell cytosol. The ABO blood group antigens are attached to the oligosaccharide chains that project over the surface of red blood cells and not within the cytosol. So, this is an incorrect answer.
Option (d) on the surface of red blood cell ribosome. The ABO blood group antigens are attached to the oligosaccharide chains that project over the surface of red blood cells. These chains are attached to proteins and lipids that lie over the surface of the red blood cell membrane and not ribosome. So, this is an incorrect answer.
Thus, the antigens related to the ABO blood group are located on the surface of the red blood cell membranes.
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Chapter 43 Solutions
Laboratory Manual For Human Anatomy & Physiology
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Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning