Connect With Learnsmart Labs Online Access For Prescott's Microbiology
11th Edition
ISBN: 9781260408997
Author: Joanne Willey
Publisher: Mcgraw-hill Higher Education (us)
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Textbook Question
Chapter 42.1, Problem 1CC
What critical limiting factors are used in the production of penicillin? Why do you think the microbe must be stressed to produce high levels of drug?
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Explain how the Kirby-Bauer method relies on diffusion of antibiotics
The type of antimicrobial drug that would be most likely to have toxic effects in
humans based on the premise of selective toxicity when treating microbial infection
would be a drug that
O 1) inhibits the synthesis of the cell wall
O 2) inhibits metabolic pathways
O 3) disrupts the cytoplasmic membrane
4) inhibits protein synthesis
5) All of the above have equal potential to be toxic
Some bacteria produce the enzyme penicillinase, which breaks the beta-lactam ring in the penicillin molecule and converts it into penicilloic acid, which is harmless to bacteria. This is an example of which of the following mechanisms of antibiotic resistance?
which option below is the answer?
Destruction or inactivation of the antibiotic by the microbe
Preventing penetration to the target site within the microbe
Alteration of the drug’s target site(s) within the microbe
None of the other four answers are correct
Rapid ejection (pumping) of the drug out of the microbial cell
Chapter 42 Solutions
Connect With Learnsmart Labs Online Access For Prescott's Microbiology
Ch. 42.1 - Why are the cells first fed lactose and then...Ch. 42.1 - What critical limiting factors are used in the...Ch. 42.1 - Prob. 2CCCh. 42.1 - What kinds of molecular changes result from...Ch. 42.1 - Prob. 4CCCh. 42.2 - Why is there interest in developing alternatives...Ch. 42.2 - What types of microbes are good candidates for the...Ch. 42.3 - What is the objective of the scale-up process and...Ch. 42.3 - What parameters can be monitored in a modern,...Ch. 42.3 - Which of the following are secondary metabolites:...
Ch. 42.4 - Why are modular genes particularly suitable as...Ch. 42.4 - Prob. 2MICh. 42.4 - Prob. 1CCCh. 42.4 - Prob. 2CCCh. 42.4 - What is metabolic engineering? Besides...Ch. 42.4 - What is high-throughput screening and why has it...Ch. 42.4 - Prob. 5CCCh. 42.5 - Prob. 1MICh. 42.5 - What is the Ti plasmid and how is it modified for...Ch. 42.5 - How is Bt toxin produced and why is it so widely...Ch. 42.5 - Prob. 3CCCh. 42.6 - Why are diatoms and magnetotactic bacteria of...Ch. 42.6 - Prob. 2CCCh. 42 - Prob. 1RCCh. 42 - Prob. 2RCCh. 42 - Prob. 3RCCh. 42 - Prob. 4RCCh. 42 - Prob. 5RCCh. 42 - Prob. 6RCCh. 42 - Prob. 7RCCh. 42 - Prob. 1ALCh. 42 - Prob. 2AL
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- Which of the following types of antimicrobial drugs make microbes more susceptible to osmotic pressure? 1) drugs that inhibit nucleic acid synthesis O 2) drugs that inhibit metabolic pathways 3) drugs that inhibit cell wall synthesis 4) drugs that block a pathogen's recognition of its host 5) drugs that inhibit protein synthesisarrow_forwardExplain this statement "Antineoplastic natural products- Ricin".please explain at your own words.arrow_forwardExplain Ricin is a antineoplastic natural products? please explain at your own words.arrow_forward
- What is the main group of microorganisms producing the most antibiotics? Describe the biochemical characteristics of this microorganism and provide TWO (2) examples of antibiotics produced by these microbes.arrow_forwardBelow, you can see a picture of an antimicrobial drug. Regarding semi-synthetic antimicrobial drug development to try to avoid development of antibiotic resistance, use 1 sentence to address what is the significance/value of the presence of the various R-groups (e.g. R4, R5, R6, etc.)?arrow_forwardWe have many antimicrobial drugs to treat bacterial infections, but very few for viruses. Why is it so difficult to treat viral infections? Hint: What would the targets for the drugs be?arrow_forward
- List four mechanisms that bacteria have developed through mutation to resist antimicrobial drugsarrow_forwardBroad-spectrum drugs target a wide variety of bacterial pathogens. Even when the broad-spectrum drug is capable of killing a target pathogen, it may not be the best treatment. Which statement best explains why a broad spectrum drug might be an undesirable treatment choice? Broad-spectrum antimicrobials are usually toxic to the host cells. Broad-spectrum antimicrobials only work if they are used shortly after the infection begins. Broad-spectrum antimicrobials may kill much of the normal microbiota. Broad-spectrum antimicrobials are not able to kill bacteria that are in their log phase of growth. Broad-spectrum antimicrobials may stimulate excess growth of the normal microbiota.arrow_forwardWhat bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.arrow_forward
- Why is the effectiveness of an antimicrobial agent determined using an exponentially growing bacterial culture? Please explain.arrow_forwardIf a bacterial isolate shows intermediate to moderate resistance to an antimicrobial, how might this drug still be successfully used in the treatment of this microbe?arrow_forwardWhat is the mechanism of an antibiotic removal device (ARD)?arrow_forward
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USMLE-Rx Antimicrobial Therapy; Author: USMLE-Rx;https://www.youtube.com/watch?v=Pka1Ynlrqtw;License: Standard Youtube License