The Living World
The Living World
9th Edition
ISBN: 9781259694042
Author: George B Johnson Professor
Publisher: McGraw-Hill Education
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Chapter 4.10, Problem 1LO
Summary Introduction

To determine: The reason due to which diffusion takes place down the concentration gradient.

Introduction: Oxygen diffuses through the transported membrane into the blood which is then various to various cells and tissues of the body. Around 98.5% of the oxygen is carried through hemoglobin, and the rest of the oxygen is present as dissolved plasma. Carbon dioxide is mainly transported through the membrane as bicarbonate ions.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

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