Principles of Biology
Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Chapter 40.1, Problem 1TYK
Summary Introduction

Introduction:

A pathogen is one such organism that depends on another organism-host to reproduce. Pathogens that are non-living and depend on external organism-hosts are ‘Viruses’. These have proteins, nucleic acids, lipids but cannot do anything unless it enters a living cell. Without living cells, the virus cannot multiply.

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22. Which of the following mutant proteins is expected to have a dominant negative effect when over-   expressed in normal cells?   a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function   b. mutant Grb2 protein that cannot bind to RTK   c. mutant RTK that lacks the extracellular domain   d. mutant PDK that has the PH domain but lost the kinase function   e. all of the above
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