ANAT & PHYS: AN INTEG APPR >LL< W/CONNEC
4th Edition
ISBN: 9781266688072
Author: McKinley
Publisher: MCG CUSTOM
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Chapter 4, Problem 8DYKB
Summary Introduction
Introduction:
The cell contains the set of proteins to regulate gene expression which is controlled at different levels; transcriptional level, and translational level. Transcription is the process by which DNA is decoded into RNA, and the translation is the process by which RNA is decoded into proteins.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 4 Solutions
ANAT & PHYS: AN INTEG APPR >LL< W/CONNEC
Ch. 4.1 - What is the advantage of using a TEM instead of an...Ch. 4.1 - Prob. 2WDYLCh. 4.1 - What are the three main structural features of a...Ch. 4.1 - What cellular structure is responsible for forming...Ch. 4.2 - How do lipids maintain the basic physical barrier...Ch. 4.2 - What type of plasma membrane protein provides the...Ch. 4.3 - How does O2 diffuse into a cell and CO2 diffuse...Ch. 4.3 - Prob. 8WDYLCh. 4.3 - Define osmosis.Ch. 4.3 - What occurs to the tonicity of a cell when it is...
Ch. 4.3 - What general conclusion can you make concerning...Ch. 4.3 - What transport process involved in the movement of...Ch. 4.3 - Diagram a flowchart for the active processes of...Ch. 4.4 - Define a resting membrane potential.Ch. 4.4 - Prob. 15WDYLCh. 4.5 - What are some examples of how cells communicate...Ch. 4.5 - How do action of enzymatic receptors and G...Ch. 4.6 - Describe the general structure of both the...Ch. 4.6 - Lysosomes and peroxisomes are both small...Ch. 4.6 - Which non-membrane-bound organelle functions (a)...Ch. 4.6 - Which cellular surface structure functions in (a)...Ch. 4.6 - Which cellular junction (a) provides resistance to...Ch. 4.7 - What is the function of nuclear pores within the...Ch. 4.7 - What is the function of the nucleolus?Ch. 4.7 - Describe the structural relationship of DNA and...Ch. 4.8 - What are the three major structures required for...Ch. 4.8 - What is a codon and an anticodon?Ch. 4.8 - How is mRNA attached to ribosomes and translated...Ch. 4.8 - The genetic code of DNA is the specific...Ch. 4.9 - How is chromatin distinguished from a chromosome?Ch. 4.9 - Describe the process of DNA replication that...Ch. 4.9 - What are the events that occur during the mitotic...Ch. 4.10 - What are the specific changes that occur to DNA...Ch. 4 - Prob. 1DYKBCh. 4 - _____ 2. The molecule that is responsible for most...Ch. 4 - Prob. 3DYKBCh. 4 - Prob. 4DYKBCh. 4 - Prob. 5DYKBCh. 4 - Prob. 6DYKBCh. 4 - Prob. 7DYKBCh. 4 - Prob. 8DYKBCh. 4 - _____ 9. During this stage of mitosis, the...Ch. 4 - _____ 10. Erythrocytes do not have a nucleus. In...Ch. 4 - Prob. 11DYKBCh. 4 - Prob. 12DYKBCh. 4 - Describe the passive processes of membrane...Ch. 4 - Describe the active processes of membrane...Ch. 4 - List the membrane-bound structures, and describe...Ch. 4 - Prob. 16DYKBCh. 4 - Prob. 17DYKBCh. 4 - Prob. 18DYKBCh. 4 - Prob. 19DYKBCh. 4 - Explain the processes that occur in the different...Ch. 4 - Michael was born with Tay-Sachs disease. Which of...Ch. 4 - Prob. 2CALCh. 4 - Prob. 3CALCh. 4 - Prob. 4CALCh. 4 - Prob. 5CALCh. 4 - Prob. 1CSLCh. 4 - Prob. 2CSLCh. 4 - Prob. 3CSL
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