The events that lead to formation of abscess. Introduction: Sepsis occurs when the body’s response to infection becomes out of control and results in damage to various tissues and organs. Sepsis is a serious condition where the blood becomes toxic due to the release of chemicals that are secreted to fight an infection in the body

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Answer 1

Question

Chapter 4, Problem 2RE

A.

Summary Introduction

To determine: The events that lead to formation of abscess.

Introduction: Sepsis occurs when the body’s response to infection becomes out of control and results in damage to various tissues and organs. Sepsis is a serious condition where the blood becomes toxic due to the release of chemicals that are secreted to fight an infection in the body

B.

Summary Introduction

To determine: The significance of incision and drainage of the lesion for healing.

Introduction: Infections are the consequence of the invasion of the normal physiological process by an infectious micro-organism. The infection is caused by the infectious substances released by such pathogens that disrupt the cells and their associated processes.

C.

Summary Introduction

To determine: The reason why antibiotics cannot work in eliminating the microorganisms contained in the abscess.

Introduction: The blood cells make up about 45% of the blood composition, and the rest of the 55% of the blood is made up of plasma. The blood cells are of three types that are red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).

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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for? 3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2

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You have a bacterial strain with the CMU operon: a) As shown in the image below, the cmu operon encodes a peptide (Pep1), as well as a kinase and regulator corresponding to a two-component system. The cmu operon is activated when Pep 1 is added to the growth media. Pep1 is a peptide that when added extracellularly leads to activation of the Cmu operon. Pep1 cmu-kinase cmu-regulator You also have these genetic components in other strains: b) An alternative sigma factor, with a promoter activated by the cmu-regulator, that control a series of multiple operons that together encode a transformasome (cellular machinery for transformation). c) the gene cl (a repressor). d) the promoter X, which includes a cl binding site (and in the absence of cl is active). e) the gene gp (encoding a green fluorescence protein). Using the cmu operon as a starting point, and assuming you can perform cloning to rearrange any of these genomic features, how would you use one or more of these to modify the…

Answer 2

Question

Chapter 4, Problem 2RE

A.

Summary Introduction

To determine: The events that lead to formation of abscess.

Introduction: Sepsis occurs when the body’s response to infection becomes out of control and results in damage to various tissues and organs. Sepsis is a serious condition where the blood becomes toxic due to the release of chemicals that are secreted to fight an infection in the body

B.

Summary Introduction

To determine: The significance of incision and drainage of the lesion for healing.

Introduction: Infections are the consequence of the invasion of the normal physiological process by an infectious micro-organism. The infection is caused by the infectious substances released by such pathogens that disrupt the cells and their associated processes.

C.

Summary Introduction

To determine: The reason why antibiotics cannot work in eliminating the microorganisms contained in the abscess.

Introduction: The blood cells make up about 45% of the blood composition, and the rest of the 55% of the blood is made up of plasma. The blood cells are of three types that are red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).

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Answer 3

Question

Chapter 4, Problem 2RE

A.

Summary Introduction

To determine: The events that lead to formation of abscess.

Introduction: Sepsis occurs when the body’s response to infection becomes out of control and results in damage to various tissues and organs. Sepsis is a serious condition where the blood becomes toxic due to the release of chemicals that are secreted to fight an infection in the body

B.

Summary Introduction

To determine: The significance of incision and drainage of the lesion for healing.

Introduction: Infections are the consequence of the invasion of the normal physiological process by an infectious micro-organism. The infection is caused by the infectious substances released by such pathogens that disrupt the cells and their associated processes.

C.

Summary Introduction

To determine: The reason why antibiotics cannot work in eliminating the microorganisms contained in the abscess.

Introduction: The blood cells make up about 45% of the blood composition, and the rest of the 55% of the blood is made up of plasma. The blood cells are of three types that are red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).

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Answer 4

Question

Chapter 4, Problem 2RE

A.

Summary Introduction

To determine: The events that lead to formation of abscess.

Introduction: Sepsis occurs when the body’s response to infection becomes out of control and results in damage to various tissues and organs. Sepsis is a serious condition where the blood becomes toxic due to the release of chemicals that are secreted to fight an infection in the body

B.

Summary Introduction

To determine: The significance of incision and drainage of the lesion for healing.

Introduction: Infections are the consequence of the invasion of the normal physiological process by an infectious micro-organism. The infection is caused by the infectious substances released by such pathogens that disrupt the cells and their associated processes.

C.

Summary Introduction

To determine: The reason why antibiotics cannot work in eliminating the microorganisms contained in the abscess.

Introduction: The blood cells make up about 45% of the blood composition, and the rest of the 55% of the blood is made up of plasma. The blood cells are of three types that are red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).

Expert Solution & Answer

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Answer 5

Chapter 4, Problem 2RE

A.

Summary Introduction

To determine: The events that lead to formation of abscess.

Introduction: Sepsis occurs when the body’s response to infection becomes out of control and results in damage to various tissues and organs. Sepsis is a serious condition where the blood becomes toxic due to the release of chemicals that are secreted to fight an infection in the body

B.

Summary Introduction

To determine: The significance of incision and drainage of the lesion for healing.

Introduction: Infections are the consequence of the invasion of the normal physiological process by an infectious micro-organism. The infection is caused by the infectious substances released by such pathogens that disrupt the cells and their associated processes.

C.

Summary Introduction

To determine: The reason why antibiotics cannot work in eliminating the microorganisms contained in the abscess.

Introduction: The blood cells make up about 45% of the blood composition, and the rest of the 55% of the blood is made up of plasma. The blood cells are of three types that are red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).

Answer 6

Chapter 4, Problem 2RE

A.

Summary Introduction

To determine: The events that lead to formation of abscess.

Introduction: Sepsis occurs when the body’s response to infection becomes out of control and results in damage to various tissues and organs. Sepsis is a serious condition where the blood becomes toxic due to the release of chemicals that are secreted to fight an infection in the body

Answer 7

Chapter 4, Problem 2RE

A.

Summary Introduction

To determine: The events that lead to formation of abscess.

Introduction: Sepsis occurs when the body’s response to infection becomes out of control and results in damage to various tissues and organs. Sepsis is a serious condition where the blood becomes toxic due to the release of chemicals that are secreted to fight an infection in the body

Answer 8

B.

Summary Introduction

To determine: The significance of incision and drainage of the lesion for healing.

Introduction: Infections are the consequence of the invasion of the normal physiological process by an infectious micro-organism. The infection is caused by the infectious substances released by such pathogens that disrupt the cells and their associated processes.

Answer 9

B.

Summary Introduction

To determine: The significance of incision and drainage of the lesion for healing.

Introduction: Infections are the consequence of the invasion of the normal physiological process by an infectious micro-organism. The infection is caused by the infectious substances released by such pathogens that disrupt the cells and their associated processes.

Answer 10

C.

Summary Introduction

To determine: The reason why antibiotics cannot work in eliminating the microorganisms contained in the abscess.

Introduction: The blood cells make up about 45% of the blood composition, and the rest of the 55% of the blood is made up of plasma. The blood cells are of three types that are red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).

Answer 11

C.

Summary Introduction

To determine: The reason why antibiotics cannot work in eliminating the microorganisms contained in the abscess.

Introduction: The blood cells make up about 45% of the blood composition, and the rest of the 55% of the blood is made up of plasma. The blood cells are of three types that are red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 4 - Prob. 1RE Ch. 4 - Prob. 2RE

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Chapter 4 Solutions