Chapter 4, Problem 22CQ

(a)

Summary Introduction

To determine: The net charge at neutral pH of a tripeptide containing only alanine.

Concept introduction: Each amino acid has unique ionization characteristics that vary at different pH levels. Ionizable groups such as amino group and carboxylic group, at certain pH levels, remain protonated, and when the pH increases, they become deprotonated.

(b)

Summary Introduction

To determine: How the total number of negative and positive charges changes, following the hydrolysis of the tripeptide containing only alanine.

Concept introduction: Each amino acid has unique ionization characteristics that vary at different pH levels. Ionizable groups such as amino group and carboxylic group at certain pH levels remain protonated, and when the pH increases, they become deprotonated.