GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS
6th Edition
ISBN: 9781260239775
Author: BROOKER
Publisher: MCG
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Chapter 4, Problem 10CONQ
A woman with type B blood has a child with type O blood. What are the possible genotypes and blood types of the father?
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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine:
(a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip
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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
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The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?
Chapter 4 Solutions
GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS
Ch. 4.1 - 1. Which of the following statements is true?
a....Ch. 4.2 - 1. Which of the following is not an example of a...Ch. 4.2 - Prob. 2COMQCh. 4.2 - 3. Polydactyly is a condition in which a person...Ch. 4.3 - The outcome of an individuals traits is controlled...Ch. 4.4 - Prob. 1COMQCh. 4.4 - Prob. 2COMQCh. 4.5 - Prob. 1COMQCh. 4.5 - Hemophilia is a blood-clotting disorder in humans...Ch. 4.6 - Prob. 1COMQ
Ch. 4.7 - 1. The Manx phenotype in cats is caused by a...Ch. 4.8 - Which of the following is a possible explanation...Ch. 4.9 - 1. Two different strains of sweet peas are...Ch. 4.9 - If the F1 offspring from question 1 are allowed to...Ch. 4 - 1. Describe the differences among dominance,...Ch. 4 - Discuss the differences among sex-influenced,...Ch. 4 - 3. What is meant by a gene interaction? How can a...Ch. 4 - Lets suppose a recessive allele encodes a...Ch. 4 - 5. A nectarine is a peach without the fuzz. The...Ch. 4 - 6. An allele in Drosophila produces a star-eye...Ch. 4 - A seed dealer wants to sell four-oclock seeds that...Ch. 4 - 8. The blood serum from one individual (let’s call...Ch. 4 - 9. Which blood type phenotypes (A, B, AB, and/or...Ch. 4 - A woman with type B blood has a child with type O...Ch. 4 - A type A woman is the daughter of a type O father...Ch. 4 - In Shorthorn cattle, coat color is controlled by a...Ch. 4 - In chickens, the Leghorn variety has white...Ch. 4 - Propose the most likely mode of inheritance...Ch. 4 - 15. A human disease known as vitamin D-resistant...Ch. 4 - 16. Hemophilia is an X-linked recessive trait in...Ch. 4 - 17. Incontinentia pigmenti, a rare, X-linked...Ch. 4 - 18. Scurs in cattle is a sex-influenced trait. A...Ch. 4 - In rabbits, the color of body fat is controlled by...Ch. 4 - Prob. 20CONQCh. 4 - 21. The trait of feathering in fowls is a...Ch. 4 - Based on the pedigree shown here for a trait...Ch. 4 - 23. The pedigree shown here involves a trait...Ch. 4 - Lets suppose you have pedigree data from thousands...Ch. 4 - Prob. 25CONQCh. 4 - 26. In humans, a very rare dominant allele that...Ch. 4 - 27. A sex-influenced trait in humans affects the...Ch. 4 - Three coat-color patterns that occur in some...Ch. 4 - Prob. 1EQCh. 4 - 2. In chickens, some varieties have feathered...Ch. 4 - 3. In sheep, the formation of horns is a...Ch. 4 - Prob. 4EQCh. 4 - In the clover butterfly, males are always yellow,...Ch. 4 - The Mic2 gene in humans is present on both the X...Ch. 4 - 7. Duroc Jersey pigs are typically red, but a...Ch. 4 - 8. As shown in Figure 4.17, coat color in rodents...Ch. 4 - 9. Summer squash exist in long, spherical, or disk...Ch. 4 - In a species of plant, two genes control flower...Ch. 4 - 11. Red eyes is the wild-type phenotype in...Ch. 4 - 12. As mentioned in Experimental Question E11, red...Ch. 4 - Lets suppose you were looking through a vial of...Ch. 4 - 14. When examining a human pedigree, what features...Ch. 4 - Lets suppose a gene exists as a functional...Ch. 4 - In oats, the color of the chaff is determined by a...
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