PRESCOTT'S MICROBILOGY
11th Edition
ISBN: 9781264075515
Author: WILLEY
Publisher: MCG
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Chapter 39.1, Problem 3CC
Summary Introduction
Corynebacterium diphtheriae is the causative agent of diphtheria, a contagious disease. Corynebacterium diphtheriae is well adapted to airborne transmissions through nasopharyngeal secretions. Mostly, diphtheria affects unimmunized people. The common symptoms of diphtheria include fever, sore throat, and barky cough. Some strains of Corynebacterium diphtheriae produce a toxin, which causes serious complications of diphtheria.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 39 Solutions
PRESCOTT'S MICROBILOGY
Ch. 39.1 - What organisms serve as the environmental...Ch. 39.1 - How is the M protein also thought to be involved...Ch. 39.1 - Prob. 3MICh. 39.1 - Why do you think chlamydiae differentiate into...Ch. 39.1 - Compare and contrast the means by which people...Ch. 39.1 - Prob. 3CCCh. 39.1 - What are the three major causes of meningitis? Why...Ch. 39.1 - Prob. 5CCCh. 39.1 - How do multidrug-resistant strains of tuberculosis...Ch. 39.1 - Prob. 7CC
Ch. 39.1 - What is the mechanism by which PTx kills host...Ch. 39.1 - Prob. 9CCCh. 39.1 - Prob. 10CCCh. 39.2 - What are the three stages of Lyme disease? What...Ch. 39.2 - Prob. 1CCCh. 39.2 - Prob. 2CCCh. 39.2 - Prob. 3CCCh. 39.2 - Prob. 4CCCh. 39.3 - What are the chief differences between tuberculoid...Ch. 39.3 - How does H. pylori increase the local pH in its...Ch. 39.3 - Prob. 3MICh. 39.3 - Prob. 4MICh. 39.3 - Prob. 5MICh. 39.3 - Prob. 1CCCh. 39.3 - Why do you think the slow growth rate of M. leprae...Ch. 39.3 - Prob. 3CCCh. 39.3 - Prob. 4CCCh. 39.3 - Prob. 5CCCh. 39.3 - Prob. 6CCCh. 39.3 - Prob. 7CCCh. 39.3 - What is the difference between S. aureus and MRSA?Ch. 39.3 - Prob. 9CCCh. 39.3 - Prob. 10CCCh. 39.3 - Prob. 11CCCh. 39.4 - How do the neurological effects of botulinum toxin...Ch. 39.4 - To which E. coli class does the strain 0157:H7...Ch. 39.4 - Prob. 1CCCh. 39.4 - Compare the gastroenteritis caused by Vibrio...Ch. 39.4 - Prob. 3CCCh. 39.4 - Prob. 4CCCh. 39.4 - Prob. 5CCCh. 39.4 - Prob. 6CCCh. 39.4 - Prob. 7CCCh. 39.5 - Prob. 1MICh. 39.5 - Prob. 1CCCh. 39.5 - Prob. 2CCCh. 39.5 - How is ornithosis transmitted?Ch. 39.5 - Prob. 4CCCh. 39.6 - What cells and tissues make up the pseudomembrane?Ch. 39.6 - Prob. 2MICh. 39.6 - In both C. difficileassociated disease and...Ch. 39.6 - Prob. 2CCCh. 39.6 - Prob. 3CCCh. 39.6 - Prob. 4CCCh. 39 - Prob. 1RCCh. 39 - Prob. 2RCCh. 39 - Prob. 3RCCh. 39 - Prob. 4RCCh. 39 - Prob. 5RCCh. 39 - Prob. 1ALCh. 39 - Prob. 2ALCh. 39 - Prob. 3ALCh. 39 - Prob. 4ALCh. 39 - Prob. 5ALCh. 39 - Prob. 6AL
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