Biochemistry
8th Edition
ISBN: 9781464126109
Author: Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr., Lubert Stryer
Publisher: W. H. Freeman
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Chapter 36, Problem 9P
Interpretation Introduction
Interpretation:
The possible application for the drug involved in the cancer chemotherapy which is capable of inhibiting the ABC transporter MDR should be determined.
Concept introduction:
ABC transporters use the ATP binding energy and hydrolysis to transport numerous substrates through the cellular membranes. These ABC transporters can be divided into three chief functional classes. In prokaryotes, importers facilitate the uptake of nutrients into the cell.
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