When a person is exposed to an antigen, for example, an infection or vaccine, there is an initial lag phase up to several weeks, but before an antibody response is mounted. No antigen-specific antibody can be noticed in the blood during the latent period. But, when B cells have differentiated into plasma cells, Igs are secreted and it can be detected. During the primary antibody response, initially IgM appears and later IgG appears. During the secondary antibody response, the primary antibody response induces the immune system. Since, it possesses immunological memory by means of memory B cells, each cell respond to various antigens.

Question

Want to see the full answer?

Answer 1

Question

Chapter 33.7, Problem 3MI

Summary Introduction

When a person is exposed to an antigen, for example, an infection or vaccine, there is an initial lag phase up to several weeks, but before an antibody response is mounted. No antigen-specific antibody can be noticed in the blood during the latent period. But, when B cells have differentiated into plasma cells, Igs are secreted and it can be detected. During the primary antibody response, initially IgM appears and later IgG appears. During the secondary antibody response, the primary antibody response induces the immune system. Since, it possesses immunological memory by means of memory B cells, each cell respond to various antigens.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Shortly after the recovery from COVID-19, the plasma of the convalescent has significant quantities of anti-SARS-CoV-2 antibodies. This plasma was suggested to be used as therapy for other COVID-19 patients by transfusing the plasma from the recovered individuals (donor) to the other COVID-19 patients (recipient). Do you think the identification of the ABO group of the donor and recipient is important and why? O a. No, this has nothing to do with blood grouping. It is only related to the virus and the antibodies against it. O b. Yes, but I really have no idea why. O c. No, not important because the antigens A, B or AB exist on the surface of red blood cells but not in the plasma and when they transfer, they do not transfer cells (only plasma) O d. Yes, because the donor plasma might contain anti-A or Anti-B or both which might induce an immune response if the recipient has A or B or AB group. Clear my choice

What is the difference in the kinetics of antibody formation in response to a dirst and second exposure to the same antigen?

Surprisingly, humans as well as mice deficient in the complement protein, C3, have greatly reduced antibody responses to T cell-dependent antigens, and are impaired in their ability to control HSV infections. When C3-deficient mice are infected with HSV, once at day 0 and then a second time 4 weeks later, their antibody response is altered compared to wild-type mice, as shown in the figure #3 below. a) What is a likely explanation for the altered antibody response in the absence of complement C3? For fugure #4: For this experiment, mice are infected with varying doses of the HSV-rd virus, and peak IgG responses to the viral surface glycoproteins are measured. The results are shown in the fugure #4. b) What is the most likely explanation for these data? Do these results impact your answer to the part above (a)? Explain your reasoning.