Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 33, Problem 4P
Interpretation Introduction
Interpretation:
The mechanism for the activation of DNA by 5-azacytidine should be explained.
Concept introduction:
5-Azacytidine is an analog of cytidine, which is a nucleoside. This chemicaland its deoxygenated analogdecitabine is used to treat myelodysplastic syndrome. High dosage of 5-azacytidine can cause anemia, thrombocytopenia, and neutropenia.
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