The most stable conformation of the piperidine derivative is to be drawn. In piperidine derivative the hydrogen bonded to nitrogen has been replaced by methyl. Concept introduction: The position of axial and equatorial bonds in cyclohexane chair form is A substituent at an equatorial position is more stable than a substituent at an axial position. A methyl group has 1-3-diaxial interactions with the substituents present on the same side of the ring (cis substituents) The van der Waals strain is greater between the axial hydrogen and the hydrogen of axial methyl group at C-3 and C-5 and negligible between the axial hydrogen at C-1 , C-3 , and C-5 .

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Answer 1

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Chapter 3.15, Problem 19P

Interpretation Introduction

Interpretation:

The most stable conformation of the piperidine derivative is to be drawn. In piperidine derivative the hydrogen bonded to nitrogen has been replaced by methyl.

Concept introduction:

The position of axial and equatorial bonds in cyclohexane chair form is

A substituent at an equatorial position is more stable than a substituent at an axial position.

A methyl group has 1-3-diaxial interactions with the substituents present on the same side of the ring (cis substituents)

The van der Waals strain is greater between the axial hydrogen and the hydrogen of axial methyl group at C-3 and C-5 and negligible between the axial hydrogen at C-1, C-3, and C-5.

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3. What are the formal charges, if any, on atoms other than carbon and hydrogen in the following molecule? H H :S=C=N-C-C-H | H H

Answer 2

Question

Chapter 3.15, Problem 19P

Interpretation Introduction

Interpretation:

The most stable conformation of the piperidine derivative is to be drawn. In piperidine derivative the hydrogen bonded to nitrogen has been replaced by methyl.

Concept introduction:

The position of axial and equatorial bonds in cyclohexane chair form is

A substituent at an equatorial position is more stable than a substituent at an axial position.

A methyl group has 1-3-diaxial interactions with the substituents present on the same side of the ring (cis substituents)

The van der Waals strain is greater between the axial hydrogen and the hydrogen of axial methyl group at C-3 and C-5 and negligible between the axial hydrogen at C-1, C-3, and C-5.

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Answer 3

Question

Chapter 3.15, Problem 19P

Interpretation Introduction

Interpretation:

The most stable conformation of the piperidine derivative is to be drawn. In piperidine derivative the hydrogen bonded to nitrogen has been replaced by methyl.

Concept introduction:

The position of axial and equatorial bonds in cyclohexane chair form is

A substituent at an equatorial position is more stable than a substituent at an axial position.

A methyl group has 1-3-diaxial interactions with the substituents present on the same side of the ring (cis substituents)

The van der Waals strain is greater between the axial hydrogen and the hydrogen of axial methyl group at C-3 and C-5 and negligible between the axial hydrogen at C-1, C-3, and C-5.

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Answer 4

Question

Chapter 3.15, Problem 19P

Interpretation Introduction

Interpretation:

The most stable conformation of the piperidine derivative is to be drawn. In piperidine derivative the hydrogen bonded to nitrogen has been replaced by methyl.

Concept introduction:

The position of axial and equatorial bonds in cyclohexane chair form is

A substituent at an equatorial position is more stable than a substituent at an axial position.

A methyl group has 1-3-diaxial interactions with the substituents present on the same side of the ring (cis substituents)

The van der Waals strain is greater between the axial hydrogen and the hydrogen of axial methyl group at C-3 and C-5 and negligible between the axial hydrogen at C-1, C-3, and C-5.

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Answer 5

Chapter 3.15, Problem 19P

Interpretation Introduction

Interpretation:

The most stable conformation of the piperidine derivative is to be drawn. In piperidine derivative the hydrogen bonded to nitrogen has been replaced by methyl.

Concept introduction:

The position of axial and equatorial bonds in cyclohexane chair form is

A substituent at an equatorial position is more stable than a substituent at an axial position.

A methyl group has 1-3-diaxial interactions with the substituents present on the same side of the ring (cis substituents)

The van der Waals strain is greater between the axial hydrogen and the hydrogen of axial methyl group at C-3 and C-5 and negligible between the axial hydrogen at C-1, C-3, and C-5.

Answer 6

Chapter 3.15, Problem 19P

Interpretation Introduction

Interpretation:

The most stable conformation of the piperidine derivative is to be drawn. In piperidine derivative the hydrogen bonded to nitrogen has been replaced by methyl.

Concept introduction:

The position of axial and equatorial bonds in cyclohexane chair form is

A substituent at an equatorial position is more stable than a substituent at an axial position.

A methyl group has 1-3-diaxial interactions with the substituents present on the same side of the ring (cis substituents)

The van der Waals strain is greater between the axial hydrogen and the hydrogen of axial methyl group at C-3 and C-5 and negligible between the axial hydrogen at C-1, C-3, and C-5.

Answer 7

Chapter 3.15, Problem 19P

Interpretation Introduction

Interpretation:

The most stable conformation of the piperidine derivative is to be drawn. In piperidine derivative the hydrogen bonded to nitrogen has been replaced by methyl.

Concept introduction:

The position of axial and equatorial bonds in cyclohexane chair form is

A substituent at an equatorial position is more stable than a substituent at an axial position.

A methyl group has 1-3-diaxial interactions with the substituents present on the same side of the ring (cis substituents)

The van der Waals strain is greater between the axial hydrogen and the hydrogen of axial methyl group at C-3 and C-5 and negligible between the axial hydrogen at C-1, C-3, and C-5.

Answer 8

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Answer 10

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Answer 11

Ch. 3.1 - Identify the alkanes corresponding to each of the...Ch. 3.1 - Find the conformations in Figure 3.4 in which the...Ch. 3.2 - Sketch a potential energy diagram for rotation...Ch. 3.2 - Acetylcholine is a neurotransmitter in the central...Ch. 3.2 - Prob. 5P Ch. 3.5 - The heats of combustion of ethylcyclopropane and...Ch. 3.8 - Prob. 7P Ch. 3.10 - The following questions relate to a cyclohexane...Ch. 3.10 - Draw the most stable conformation of...Ch. 3.11 - Prob. 10P

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