BIOCHEM-ACHIEVE(FIRST DAY DISCOUNTED)
BIOCHEM-ACHIEVE(FIRST DAY DISCOUNTED)
9th Edition
ISBN: 2818000069358
Author: BERG
Publisher: MAC HIGHER
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Chapter 31, Problem 21P
Interpretation Introduction

Interpretation:

An affinity-labeling reagent for the tRNA binding sites in E. coli ribosomes should be determined.

Concept introduction:

The inhibitor that formsa covalent bond with its target (basically an enzyme) and inactivates it, is termed as the affinity label. The basic mechanism of the affinity label is to specifically and reversible deliver a weak reactive group to enzyme that can irreversibly binds to an amino acid residue.

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