Biochemistry
6th Edition
ISBN: 9781337359573
Author: Reginald H. Garrett; Charles M. Grisham
Publisher: Cengage Learning US
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Chapter 31, Problem 16P
Interpretation Introduction
Interpretation :
At least eight other post-translational modifications and the amino acid residues involved in post translational protein modifications needs to be determined.
Concept Introduction :
The covalent and the enzymatic proteins modification subsequent to protein biosynthesis are known as PTM i.e. Post-translational modification. The ribosomes translate mRNA into polypeptide chains to synthesize proteins that can undergo post-translational modification to produce the protein product that is comparatively mature.
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Four distinct classes of interactions (inter and intramolecular forces) contribute to a protein's tertiary and quaternary structures. Name the interaction then describe the amino acids that can form this type of interaction. Draw and annotate a diagram of the interaction between two amino acids.
Examine the metabolic pathway. The enzymes that catalyze each step are identified as "e" with a numeric subscript.
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Which of the enzymes is likely to be the allosteric
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An allosteric enzyme that follows the concerted model has an allosteric coefficient (T/R) of 300 in the absence of substrate.
Suppose that a mutation reversed the ratio.
Select the effects this mutation will have on the relationship between the rate of the reaction (V) and substrate
concentration, [S].
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The enzyme would likely follow Michaelis-Menten kinetics.
The plot of V versus [S] would be sigmoidal.
The enzyme would mostly be in the T form.
The plot of V versus [S] would be hyperbolic.
The enzyme would be more active.
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