WHAT IS LIFE W/LAUNCHPAD
WHAT IS LIFE W/LAUNCHPAD
3rd Edition
ISBN: 9781319059705
Author: PHELAN
Publisher: Macmillan Higher Education
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Chapter 3, Problem 6MC
Summary Introduction

Introduction:

Cellular fingerprints are made of the various molecules on the cell surface and vary among cell types.

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"One of the symmetry breaking events in mouse gastrulation requires the amplification of Nodal on the side of the embryo opposite to the Anterior Visceral Endoderm (AVE). Describe one way by which Nodal gets amplified in this region." My understanding of this is that there are a few ways nodal is amplified though I'm not sure if this is specifically occurs on the opposite side of the AVE.  1. pronodal cleaved by protease -> active nodal 2. Nodal -> BMP4 -> Wnt-> nodal 3. Nodal-> Nodal, Fox1 binding site  4. BMP4 on outside-> nodal  Are all of these occuring opposite to AVE?
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