BIOLOGY: CONCEPTS AND INVESTIGATIONS,
BIOLOGY: CONCEPTS AND INVESTIGATIONS,
5th Edition
ISBN: 9781266382307
Author: Hoefnagels
Publisher: MCG
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Chapter 3, Problem 5MCQ
Summary Introduction

Introduction:

The organs with a lumen have different molecules in it that are undergoing various reactions. So, a molecule entering the lumen or even leaving the lumen will hinder the reaction. Thus, the epithelial cells here have a tight junction to halt any such unwanted movements of molecules.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

Chapter 3 Solutions

BIOLOGY: CONCEPTS AND INVESTIGATIONS,

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