Anatomy & Physiology
3rd Edition
ISBN: 9781259398629
Author: McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher: Mcgraw Hill Education,
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Textbook Question
Chapter 3, Problem 4DYB
ATP inhibits phosphofructokinase by binding to an allosteric site in glycolysis. ATP is functioning as a
- a. competitive inhibitor.
- b. competitive activator.
- c. noncompetitive inhibitor.
- d. noncompetitive activator.
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ATP inhibits glycolysis by binding to an allosteric site on the last enzyme In the pathway, thus ATP is a...
A. Competitive inhibitor
B. Noncompetitive inhibitor
C. Feedback inhibitor
D. More than one of these answers.
Please give the rationale as to why
One of the enzymes involved in glycolysis, aldolase, requires Zn2+ for catalysis. Under conditions of zinc deficiency and the enzyme lacks zinc, it would be referred to as the:
a. apoenzyme.
b. coenzyme.
c. holoenzyme.
d. prosthetic group.
e. substrate.
Which of the following statements concerning the enzyme regulation is CORRECT?
Select one:
A.
Citrate is the allosteric inhibitor of hexokinase.
B.
AMP is the alloseric activator of pyruvate dehydrogenase.
C.
Glucose-6-phosphate is the allosteric activator for phosphofructokinase.
D.
ATP is the activator of pyruvate kinase.
Chapter 3 Solutions
Anatomy & Physiology
Ch. 3.1 - LEARNING OBJECTIVE
1. Describe the two classes of...Ch. 3.1 - Prob. 1WDLCh. 3.1 - LEARNING OBJECTIVES
2. Describe chemical energy...Ch. 3.1 - Prob. 3LOCh. 3.1 - Muscle contraction is an example of what form of...Ch. 3.1 - Prob. 4LOCh. 3.1 - Prob. 5LOCh. 3.1 - Prob. 3WDLCh. 3.2 - Prob. 6LOCh. 3.2 - Prob. 7LO
Ch. 3.2 - Prob. 4WDLCh. 3.2 - Prob. 8LOCh. 3.2 - Prob. 9LOCh. 3.2 - Prob. 10LOCh. 3.2 - Prob. 11LOCh. 3.2 - Prob. 1WDTCh. 3.2 - For a biochemical reaction that involves simple...Ch. 3.2 - Prob. 6WDLCh. 3.2 - Explain what occurs when the equilibrium is...Ch. 3.2 - Prob. 12LOCh. 3.2 - Prob. 13LOCh. 3.2 - Explain the effect a fever would have on chemical...Ch. 3.2 - Prob. 14LOCh. 3.3 - What is the relationship of enzymes and activation...Ch. 3.3 - Prob. 15LOCh. 3.3 - Prob. 16LOCh. 3.3 - What is the active site of an enzyme and how does...Ch. 3.3 - Prob. 17LOCh. 3.3 - Prob. 18LOCh. 3.3 - What is the mechanism of enzyme action, including...Ch. 3.3 - Prob. 19LOCh. 3.3 - LEARNING OBJECTIVES
20. Describe the naming...Ch. 3.3 - Prob. 2WDTCh. 3.3 - Explain how enzymes are generally named.Ch. 3.3 - Prob. 21LOCh. 3.3 - LEARNING OBJECTIVES
22. Explain the effect of...Ch. 3.3 - Prob. 23LOCh. 3.3 - How do changes in substrate concentration,...Ch. 3.3 - Prob. 24LOCh. 3.3 - How are enzymes regulated through competitive and...Ch. 3.3 - Prob. 25LOCh. 3.3 - LEARNING OBJECTIVES
26. Explain the role of...Ch. 3.3 - LEARNING OBJECTIVES
27. Identify and explain the...Ch. 3.3 - Prob. 15WDLCh. 3.3 - Prob. 16WDLCh. 3.4 - Prob. 28LOCh. 3.4 - LEARNING OBJECTIVES
29. Name the two pathways...Ch. 3.4 - Prob. 30LOCh. 3.4 - Prob. 17WDLCh. 3.4 - Prob. 18WDLCh. 3.4 - Prob. 31LOCh. 3.4 - Prob. 3WDTCh. 3.4 - Prob. 19WDLCh. 3.4 - Prob. 20WDLCh. 3.4 - LEARNING OBJECTIVES
32. Explain the enzymatic...Ch. 3.4 - Prob. 33LOCh. 3.4 - Prob. 21WDLCh. 3.4 - Prob. 34LOCh. 3.4 - Prob. 4WDTCh. 3.4 - Prob. 22WDLCh. 3.4 - Prob. 23WDLCh. 3.4 - Prob. 35LOCh. 3.4 - Prob. 36LOCh. 3.4 - Prob. 24WDLCh. 3.4 - Prob. 25WDLCh. 3.4 - LEARNING OBJECTIVES
37. Calculate the number of...Ch. 3.4 - WHAT DO YOU THINK?
5 Given that energy from each...Ch. 3.4 - Prob. 26WDLCh. 3.4 - LEARNING OBJECTIVES
38. Explain the fate of...Ch. 3.4 - Prob. 39LOCh. 3.4 - Prob. 27WDLCh. 3.4 - Prob. 40LOCh. 3.4 - Prob. 28WDLCh. 3 - Energy in ATP is used to power skeletal muscle...Ch. 3 - Prob. 2DYBCh. 3 - Prob. 3DYBCh. 3 - ATP inhibits phosphofructokinase by binding to an...Ch. 3 - All of the following are accurate about enzymes...Ch. 3 - Prob. 6DYBCh. 3 - Prob. 7DYBCh. 3 - All stages of cellular respiration are decreased...Ch. 3 - Prob. 9DYBCh. 3 - Prob. 10DYBCh. 3 - Prob. 11DYBCh. 3 - Describe the different ways of classifying...Ch. 3 - Prob. 13DYBCh. 3 - Describe the structure and mechanism of enzymes.Ch. 3 - Prob. 15DYBCh. 3 - Prob. 16DYBCh. 3 - In general terms, explain the fate of pyruvate if...Ch. 3 - Describe how oxygen becomes part of water during...Ch. 3 - Identify the source of carbon in carbon dioxide.Ch. 3 - Prob. 20DYBCh. 3 - Prob. 1CALCh. 3 - Prob. 2CALCh. 3 - Another challenge to a patient with impaired...Ch. 3 - Prob. 4CALCh. 3 - Prob. 5CALCh. 3 - Prob. 1CSLCh. 3 - Prob. 2CSLCh. 3 - What occurs to the amount of product formed in a...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which of the following statements concerning ATP synthesis is NOT true? a. The open conformation of the ATP synthase is for releasing ATP. b. The gamma subunit in the stalk responds to the flow of H+ and rotates the assembly counterclockwise and thus change the conformations of the active site to synthesize ATP. c. The tight conformation of the ATP synthase is for converting ADP and phosphate to ATP. d. The loose conformation of the ATP synthase is for binding ADP and phosphate. e. Ten protons are required to catalyze the rotation of the subunits so that one ATP is synthesized. Clear my choicearrow_forwardIn the first stage of glycolysis, the hydroxyl group on C6 of glucose is phosphorylated to form glucose-6-phosphate (G6P). In this reaction, which of the following statements is true? a. O b. d. e. Glucose kinase is used to catalyze the reaction. Hexokinase is used to catalyze the reaction. A molecule of NADH is synthesized. One ATP is synthesized. Fructose kinase is used to catalyze the reaction.arrow_forwardRapidly dividing cells such as bone marrow, skin, intestinal mucosa, and cancer cells need DNA synthesis. In these cells, the following is observed: a. a decreased NADPH / NADP+ ratio b. increased flux through the oxidative reactions c. Flux through the oxidative reactions is low and the nonoxidative reactions are reversed to make ribose 5-phosphate. d. Ribose 5-phosphate is recycled through the oxidative steps via the nonoxidative reactions and gluconeogenesis. e. Ribose 5-phosphate is shunted into glycolysis by the nonoxidative reactions.arrow_forward
- Which of the following statements is correct? a. Glycolysis and Krebs cycle produce ATP in substrate level phosphorylation b. Glycolysis and Krebs cycle produce ATP in oxidative level phosphorylation. c. Glycolysis and pyruvate oxidation produce ATP in substrate level phosphorylation. d. Glycolysis and pyruvate oxidation produce ATP in oxidative level phosphorylation.arrow_forwardGlycolysis is regulated primarily by _______________. a. three strongly exergonic, non-equilibrium reactions. b. three strongly endergonic, non-equilibrium reactions. c. allosteric effectors of pyruvate kinase. d. phosphorylation of phosphofructokinase. e. the availability of glucose-6-phosphate.arrow_forwardWhich of the following is incorrect about the ATP synthase mechanism? a. It explains how ATP is hydrolyzed into ADP and Pi b. At any moment, each catalytic site has a different conformation and binding affinity c. It is called the binding change mechanism d. It involves rotation-driven conformational changes that alter the affinity of each catalytic subunitarrow_forward
- Identify in which reactions in glycolysis the followingfunctions occur.a. ATP consumptionb. ATP synthesisc. NADH synthesisarrow_forwardATP production is limited from glycolysis in strenuously exercising muscle or when yeast are fermenting carbohydrates in closed vessels. The limiting factor is Select one: a. the increased acidity from lactic acid causing muscle damage b. the accumulation of CO, c. the lack of ATP to continue glycolysis d. the lack of organic fuel molecules to oxidize e. the need to regenerate NAD+arrow_forwardWhich of the following enzymes is the key regulatory step in glycolysis? Phosphofructiokinase-1 is the answer. Explain? A. Phosphoglucose Isomerase B. Phosphofructokinase-1 C. Pyruvate Kinase D. Hexokiase E. Phosphofructokinase-2 ...Why is Phosphoglucose Isomerase wrong?arrow_forward
- Which of the following is FALSE about glycolysis? a. The pathway axidizes two moles of NADH to NAD* for each mole of glucose. b. The pathway requires two moles of ATP to get started catabolizing each mole of glucose. c. ADP is phosphorylated to ATP via substrate -level phosphorylation. d. The pattivay produces pyruvate as one of its products.arrow_forwardWhat is / are the advantages of having a step by step breakdown pathway? Select all the correct answers. Select one or more: a.Creates multiple point of regulation b.controlled capture of released energy c.multiple entry points for breakdown substrates d.generates intermediates that can be used in anabolic metabolismarrow_forwardThe first reaction in glycolysis that results in the formation of an energy-rich compound (i.e., a compound whose hydrolysis or oxidation has a highly negative ΔG'°) is catalyzed by: a. glyceraldehyde 3-phosphate dehydrogenase. b. hexokinase. c. phosphofructokinase-1. d. phosphoglycerate kinase. e. triose phosphate isomerase.arrow_forward
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