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Essentials of Human Anatomy & Physiology Laboratory Manual (6th Edition)
6th Edition
ISBN: 9780321947918
Author: Elaine N. Marieb
Publisher: PEARSON
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Textbook Question
Chapter 3, Problem 36CAQ
Hydrocortisone is an anti-inflammatory drug that stabilizes lysosomal membranes. Explain how this effect reduces cell damage and inflammation.
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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…
The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?
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Chapter 3 Solutions
Essentials of Human Anatomy & Physiology Laboratory Manual (6th Edition)
Ch. 3 - More than one choice may apply. Which of the...Ch. 3 - More than one choice may apply. Which of the...Ch. 3 - Which of the following are possible functions of...Ch. 3 - 4. A cell with abundant peroxisomes would most...Ch. 3 - A cell stimulated to increase its steroid...Ch. 3 - More than one choice may apply. For osmosis to...Ch. 3 - More than one choice may apply. Which of the...Ch. 3 - Which epithelium is “built” to withstand friction?...Ch. 3 - 9. What kind of connective tissue acts as a...Ch. 3 - What type of connective tissue prevents muscles...
Ch. 3 - Which of the following terms describe cardiac...Ch. 3 - More than one choice may apply. Which of the...Ch. 3 - Describe the difference between a cell and an...Ch. 3 - Describe the difference between chromatin and...Ch. 3 - Describe the structure and function of plasma...Ch. 3 - 16. Describe the four structural components of the...Ch. 3 - Prob. 17SAECh. 3 - Identify the function of lysosomes.Ch. 3 - Explain the effect of the following solutions on...Ch. 3 - Prob. 20SAECh. 3 - Define mitosis. Why is mitosis important?Ch. 3 - Prob. 22SAECh. 3 - Prob. 23SAECh. 3 - 24. Why can an organ be permanently damaged if its...Ch. 3 - Describe the relative roles of DNA and RNA in...Ch. 3 - Define tissue. List the four major types of...Ch. 3 - Describe the general characteristics of epithelial...Ch. 3 - What is the function of transitional epithelium,...Ch. 3 - What are the general structural characteristics of...Ch. 3 - Describe the composition and the role of ground...Ch. 3 - Prob. 31SAECh. 3 - 32. Tell where each of the three types of muscle...Ch. 3 - 33. How does tissue healing by fibrosis differ...Ch. 3 - Prob. 34SAECh. 3 - Two examples of chemotherapeutic drugs (used to...Ch. 3 - Hydrocortisone is an anti-inflammatory drug that...Ch. 3 - Prob. 37CAQCh. 3 - 39. Three patients in an intensive care unit are...Ch. 3 - 40. Michael had a nervous habit of chewing on the...Ch. 3 - 41. Think carefully about the chemistry of the...
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