Fundamentals of Anatomy & Physiology Plus Mastering A&P with eText - Access Card Package (10th Edition) (New A&P Titles by Ric Martini and Judi Nath)
10th Edition
ISBN: 9780321908599
Author: Frederic H. Martini, Judi L. Nath, Edwin F. Bartholomew
Publisher: PEARSON
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Chapter 3, Problem 15CP
What process would be affected by the lack of the enzyme RNA polymerase?
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
(a) k, C0, V, and AUC* for the bolus iv data
(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
Chapter 3 Solutions
Fundamentals of Anatomy & Physiology Plus Mastering A&P with eText - Access Card Package (10th Edition) (New A&P Titles by Ric Martini and Judi Nath)
Ch. 3 - List the general functions of the plasma membrane.Ch. 3 - Identify the components of the plasma membrane...Ch. 3 - Which component of the plasma membrane is...Ch. 3 - Which type of integral protein allows water, ions,...Ch. 3 - Prob. 5CPCh. 3 - What are the major differences between cytosol and...Ch. 3 - Prob. 7CPCh. 3 - Prob. 8CPCh. 3 - Explain why certain cells in the ovaries and...Ch. 3 - What does the presence of many mitochondria imply...
Ch. 3 - Describe the contents and structure of the...Ch. 3 - What is a gene?Ch. 3 - Define gene activation.Ch. 3 - Describe transcription and translation.Ch. 3 - What process would be affected by the lack of the...Ch. 3 - What is meant by the term selectively permeable...Ch. 3 - Define diffusion.Ch. 3 - List five factors that influence the diffusion of...Ch. 3 - How would a decrease in the concentration of...Ch. 3 - Define osmosis.Ch. 3 - Some pediatricians recommend using a 10 percent...Ch. 3 - Describe the process of carrier-mediated...Ch. 3 - The concentration of hydrogen ions (H+) in the...Ch. 3 - Describe endocytosis.Ch. 3 - Describe exocytosis.Ch. 3 - What is the process called whereby certain types...Ch. 3 - What is the membrane potential of a cell, and in...Ch. 3 - If the plasma membrane of a cell were freely...Ch. 3 - Give the biological terms for (a) cellular...Ch. 3 - What enzymes must be present for DNA replication...Ch. 3 - Describe interphase, and identify its stages.Ch. 3 - A cell is actively manufacturing enough organelles...Ch. 3 - Define mitosis, and list its four stages.Ch. 3 - What would happen if spindle fibers failed to form...Ch. 3 - Define growth factor, and identify several growth...Ch. 3 - An illness characterized by mutations that disrupt...Ch. 3 - Define metastasis.Ch. 3 - Define cellular differentiation.Ch. 3 - Prob. 1RQCh. 3 - The process that transports solid objects such as...Ch. 3 - Plasma membranes are said to be (a) impermeable,...Ch. 3 - _____ ion concentration is high in extracellular...Ch. 3 - At resting membrane potential, the cytoplasmic...Ch. 3 - The organelle responsible for a variety of...Ch. 3 - The synthesis of a functional polypeptide using...Ch. 3 - Prob. 8RQCh. 3 - The movement of water across a membrane from an...Ch. 3 - Prob. 10RQCh. 3 - List the four basic concepts that make up the cell...Ch. 3 - What are four general functions of the plasma...Ch. 3 - What are the primary functions of membrane...Ch. 3 - By what three major transport mechanisms do...Ch. 3 - List five important factors that influence...Ch. 3 - What are the four major functions of the...Ch. 3 - Diffusion is important in body fluids, because it...Ch. 3 - Microvilli are found (a) mostly in muscle cells,...Ch. 3 - When a cell is placed in a(n) _____ solution, the...Ch. 3 - Suppose that a DNA segment has the following...Ch. 3 - Prob. 21RQCh. 3 - The sodium-potassium exchange pump (a) is an...Ch. 3 - If a cell lacked ribosomes, it would not be able...Ch. 3 - List, in sequence, the phases of the interphase...Ch. 3 - List the stages of mitosis, and briefly describe...Ch. 3 - (a) What is cytokinesis? (b) What is the role of...Ch. 3 - The transport of a certain molecule exhibits the...Ch. 3 - Solutions A and B are separated by a selectively...Ch. 3 - A molecule that blocks the ion channels lining...Ch. 3 - What is the benefit of having some of the cellular...Ch. 3 - List the general functions of the plasma membrane.Ch. 3 - Identify the components of the plasma membrane...
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