Lehninger Principles of Biochemistry (Instructor's)
Lehninger Principles of Biochemistry (Instructor's)
7th Edition
ISBN: 9781319117689
Author: nelson
Publisher: MAC HIGHER
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Chapter 3, Problem 12P
Summary Introduction

To predict: The pI for pepsin proteins.

Introduction:

Isoelectric point (pI) refers to the pH at which the net charge of a molecule becomes zero or the molecule becomes electrically neutral.

Summary Introduction

To determine: The functional groups that must be present to confer this pI on pepsin.

Introduction:

Isoelectric point (pI) refers to the pH at which the net charge of a molecule becomes zero or the molecule becomes electrically neutral.

Summary Introduction

To determine: The amino acids in proteins that would contribute the functional groups.

Introduction:

Amino acids are the monomer units of proteins. These are basically organic compounds consisting of a carboxylic group (-COOH-) and an amino group (-NH2). Along with these functional groups, a side chain (R group) is also present in all the amino acids.

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Is the structural form shown possible given the pKa constraints of the side chains?
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Identify the structure of the PTH derivative generated after two rounds of Edman degradation.
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