Chapter 29.SE, Problem 25MP

Interpretation Introduction

Interpretation:

The amino acid tyrosine is biologically degraded by a series of steps that include the following transformations:

Concept introduction:

α-amino acid, in addition to their role as proton monomeric units, are energy metabolism and processor of many biologically important nitrogen containing compounds. Notably-heme, physiologically active amine, glutathione, nucleotides and nucleotide enzyme. Amino acid are classified as

1) Essential amino acid

2) Non essential amino acid

While the non essential amino acid can be synchronized from metabolic processor, the essential amino acid must be provide by the diet. However, the essential dietary amino acid, instead of being extract or stored for future use, are converted to common metabolic intermediate like pyruvate, oxaloacetate, acetyl CoA, α-ketoglutarate etc. Thus amino acid are also precious of glucose, fatty acid, and ketone bodies and are metabolic fuel.

For the present, tyrosine clarifies itself to be a non essential amino acid, it is thus a metabolic processor and need not be supplied by the diet.

Further tyrisone is alos both a glucogenic and ketogenic amino acid. Its carbon skeleton can be degraded to either of pyruvate, α-ketoglutarate acetyl CoA, fumarate or oxaloacetate glucogenic amino acid and also to acetyl CoA or aceto acetate to be converted to ketone bodies or fatty acid. (ketogenic amino acid)

Degradation of amino acids to one of seven common metabolic intermediates