Theories of senescence including replicative senescence and the telomere theory; protein and DNA cross-linking; protein misfolding and other structural defects; the free radical theory; and the autoimmune theory. Introduction: As a result of aging, degeneration of an organ system occurs, and it is referred to as senescence. Degeneration occurs after the age of highest functional efficiency, such as reduced ability to repair damage, increased susceptibility to disease, gradual loss of reserve capacities, and compensate for stress.

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Chapter 29.4, Problem 16AYLO

Summary Introduction

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Theories of senescence including replicative senescence and the telomere theory; protein and DNA cross-linking; protein misfolding and other structural defects; the free radical theory; and the autoimmune theory.

Introduction:

As a result of aging, degeneration of an organ system occurs, and it is referred to as senescence. Degeneration occurs after the age of highest functional efficiency, such as reduced ability to repair damage, increased susceptibility to disease, gradual loss of reserve capacities, and compensate for stress.

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