PRESCOTT'S MICROBIOLOGY
PRESCOTT'S MICROBIOLOGY
11th Edition
ISBN: 2818440045677
Author: WILLEY
Publisher: MCG
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Chapter 29.1, Problem 3CC

Describe the rationale upon which the extinction culture technique is based.

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"One of the symmetry breaking events in mouse gastrulation requires the amplification of Nodal on the side of the embryo opposite to the Anterior Visceral Endoderm (AVE). Describe one way by which Nodal gets amplified in this region." My understanding of this is that there are a few ways nodal is amplified though I'm not sure if this is specifically occurs on the opposite side of the AVE.  1. pronodal cleaved by protease -> active nodal 2. Nodal -> BMP4 -> Wnt-> nodal 3. Nodal-> Nodal, Fox1 binding site  4. BMP4 on outside-> nodal  Are all of these occuring opposite to AVE?
If four babies are born on a given day What is the chance all four will be girls? Use genetics laws
Explain each punnet square results (genotypes and probabilities)
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