Package: Loose Leaf for Organic Chemistry with Biological Topics with Connect Access Card

5th Edition

ISBN: 9781260170405

Author: SMITH

Publisher: MCG

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Neutral Amino Acids

Amino acids which do not have any charge on them are neutral amino acids.

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The globular proteins refer to the shape of protein specifically spherical in nature apart from spherical form fibrous, disordered and membrane-bound proteins exist. These globular proteins are miscible in water and form a colloidal solution rather than …

Dimer

Dimers are basic organic compounds, which are derivates of oligomers. It is formed by the combination of two monomers which could potentially be strong or weak and in most cases covalent or intermolecular in nature. Identical monomers are called homodime…

Dipeptide

A dipeptide is considered a mixture of two distinct amino acids. Since the amino acids are distinct, based on their composition, two dipeptide's isomers can be produced. Various dipeptides are biologically essential and are therefore crucial to industry.

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Textbook Question

Chapter 29, Problem 29.64P

Another method to form a peptide bond involves a two-step process:

[1] Conversion of a Boc-protected amino acid to a p-nitrophenyl ester.

[2] Reaction of the p-nitrophenyl ester with an amino acid ester.

Chapter 29, Problem 29.64P, 29.64 Another method to form a peptide bond involves a two-step process:
[1] Conversion of a , example 1

a. Why does a p-nitrophenyl ester “activate” the carboxy group of the first amino acid to amide formation?

b. Would a p-methoxy phenyl ester perform the same function? Why or why not?

Chapter 29, Problem 29.64P, 29.64 Another method to form a peptide bond involves a two-step process:
[1] Conversion of a , example 2

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Chapter 29, Problem 29.63P

Chapter 29, Problem 29.65P

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Chapter 29 Solutions

Package: Loose Leaf for Organic Chemistry with Biological Topics with Connect Access Card

Ch. 29 - Prob. 29.1P Ch. 29 - Problem 29.2 What form exists at the isoelectric...Ch. 29 - Problem 29.3 Explain why the of the group of an...Ch. 29 - Prob. 29.4P Ch. 29 - Problem 29.5 What -halo carbonyl compound is...Ch. 29 - Problem 29.6 The enolate derived from diethyl...Ch. 29 - Problem 29.7 What amino acid is formed when is...Ch. 29 - Problem 29.8 What aldehyde is needed to synthesize...Ch. 29 - Problem 29.9 Draw the products of each...Ch. 29 - Prob. 29.10P

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Solution Summary: The author explains how a p- nitrophenyl ester activates the carboxy group of the first amino acid by withdrawing the electron density of carbon-oxygen bond towards itself.

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Chapter 29 Solutions