HUMAN A&P LL W/MOD.MAST.TCC ACCESS >IB<
HUMAN A&P LL W/MOD.MAST.TCC ACCESS >IB<
11th Edition
ISBN: 9781323847572
Author: Marieb
Publisher: Pearson Custom Publishing
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Chapter 29, Problem 11RQ
Summary Introduction

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The pedigree and display the phenotype and genotype for each individual.

Introduction:

Syndactyly refers to the condition in which two more digits are united together and is observed in mammals like siamang. This condition is an unusual condition in humans. This condition can be either complex or simple. In simple one, the neighboring fingers are connected soft tissue while in complex one, the bones of the nearby digits are joined. This condition is seen in Paul, his three brothers, his father, and his paternal grandmother.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.
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