Whether it is desirable to increase or decrease the proportion of hexane as the column in eluted while preparing a hexane-acetone gradient for an alumina HPLC column. Concept introduction: High-performance liquid chromatography (HPLC) is a column chromatography, which is used to separate the components of the dissolved solution. The alumina is a stationary phase of the liquid which is found in packed tubes.

Question

Protecting Groups and Carbonyls 6) The synthesis generates allethrolone that exhibits high insect toxicity but low mammalian toxicity. They are used in pet shampoo, human lice shampoo, and industrial sprays for insects and mosquitos. Propose detailed mechanistic steps to generate the allethrolone label the different types of reagents (Grignard, acid/base protonation, acid/base deprotonation, reduction, oxidation, witting, aldol condensation, Robinson annulation, etc.) III + VI HS HS H+ CH,CH,Li III I II IV CI + P(Ph)3 V ༼ Hint: no strong base added VI S VII IX HO VIII -MgBr HgCl2,HgO HO. isomerization aqeuous solution H,SO, ༽༽༤༽༽ X MeOH Hint: enhances selectivity for reaction at the S X ☑

Answer 1

Question

Chapter 28, Problem 28.5QAP

Interpretation Introduction

Interpretation:

Whether it is desirable to increase or decrease the proportion of hexane as the column in eluted while preparing a hexane-acetone gradient for an alumina HPLC column.

Concept introduction:

High-performance liquid chromatography (HPLC) is a column chromatography, which is used to separate the components of the dissolved solution. The alumina is a stationary phase of the liquid which is found in packed tubes.

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Protecting Groups and Carbonyls 6) The synthesis generates allethrolone that exhibits high insect toxicity but low mammalian toxicity. They are used in pet shampoo, human lice shampoo, and industrial sprays for insects and mosquitos. Propose detailed mechanistic steps to generate the allethrolone label the different types of reagents (Grignard, acid/base protonation, acid/base deprotonation, reduction, oxidation, witting, aldol condensation, Robinson annulation, etc.) III + VI HS HS H+ CH,CH,Li III I II IV CI + P(Ph)3 V ༼ Hint: no strong base added VI S VII IX HO VIII -MgBr HgCl2,HgO HO. isomerization aqeuous solution H,SO, ༽༽༤༽༽ X MeOH Hint: enhances selectivity for reaction at the S X ☑

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