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Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 28, Problem 24CTQ
Describe the different cell types and their functions in sponges.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 28 Solutions
Biology 2e
Ch. 28 - Figure 28.3 Which of the following statements is...Ch. 28 - Figure 28.21 Which of the following statements...Ch. 28 - Figure 28.45 Which of the following statements...Ch. 28 - Mesohyl contains: a polysaccharide gel and dead...Ch. 28 - The large central opening in the parazoan body is...Ch. 28 - Most sponge body plans are slight variations on a...Ch. 28 - Cnidocytes are found in phylum Porifera phylum...Ch. 28 - Cubozoans are polyps medusoids polymorphs spongesCh. 28 - While collecting specimens, a marine biologist...Ch. 28 - Which group of fllatworms are primarily...
Ch. 28 - The rhynchocoel is a. circulatory system...Ch. 28 - Annelids have (a): pseudocoelom true coelom no...Ch. 28 - A mantle and mantle cavity are present in: phylum...Ch. 28 - How does segmentation enhance annelid locomotion?...Ch. 28 - The embryonic development in nematodes can have up...Ch. 28 - The nematode cuticle contains. glucose skin cells...Ch. 28 - Crustaceans are ecdysozoans nematodes arachnids...Ch. 28 - Flies are ___________ . chelicerates hexapods...Ch. 28 - Which of the following is not a key advantage...Ch. 28 - Echinoderms have. triangular symmetry radial...Ch. 28 - The circulatory fluid in echinoderms is blood...Ch. 28 - Which of the following features does not...Ch. 28 - The sister taxon of the Chordata is the. Mollusca...Ch. 28 - Describe the different cell types and their...Ch. 28 - Describe the feeding mechanism of sponges and...Ch. 28 - Explain the function of nematocysts in cnidarians.Ch. 28 - Compare the structural differences between...Ch. 28 - Compare the differences in sexual reproduction...Ch. 28 - How does the tapeworm body plan support widespread...Ch. 28 - Describe the morphology and anatomy of mollusks.Ch. 28 - What are the anatomical differences between...Ch. 28 - How does a change in the circulatory system...Ch. 28 - Enumerate features of Caenoihabditis elegans that...Ch. 28 - What are the different ways in which nematodes can...Ch. 28 - Why are tardigrades essential to recolonizing...Ch. 28 - Describe the various superclasses that phylum...Ch. 28 - Compare and contrast the segmentation seen in...Ch. 28 - How do terrestrial arthropods of the subphylum...Ch. 28 - Describe the different classes of echinoderms...
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