Human Anatomy & Physiology Plus Modified Mastering A&P with Pearson eText -- Access Card Package 11th edition
11th Edition
ISBN: 9780135175040
Author: Marieb
Publisher: PEARSON
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Chapter 27, Problem 5CCS
23-Year-Old Female with Menstrual Irregularity
Jasmine Herrera, 23, has been referred to the endocrinology clinic. She is very overweight, with obvious acne and facial hair. She complains of irregular menstrual cycles. “My husband and I want to use the rhythm method," she says, “but I don’t have any rhythm!”
5. Jasmine’s blood tests reveal very high levels of androgens. She is diagnosed with polycystic ovary syndrome (PCOS). In this syndrome, the woman develops high levels of androgens and many vesicular follicles, but has reduced fertility because few follicles are ovulated and the timing of their release is unpredictable. Part of the profile of PCOS is that LH levels are high. How would this lead to androgen excess, and what clinical evidence of androgen excess does Jasmine have?
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
(a) k, C0, V, and AUC* for the bolus iv data
(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
Chapter 27 Solutions
Human Anatomy & Physiology Plus Modified Mastering A&P with Pearson eText -- Access Card Package 11th edition
Ch. 27 - Prob. 3RQCh. 27 - 2. The usual site of embryo implantation is (a)...Ch. 27 - 4. Which of the following is correct relative to...Ch. 27 - 5. Secondary sex characteristics are (a) present...Ch. 27 - 6. Which of the following produces the male sex...Ch. 27 - 7. Which will occur as a result of nondescent of...Ch. 27 - Prob. 1RQCh. 27 - 9. Relative to differences between mitosis and...Ch. 27 - 10. Match the key choices with the descriptive...Ch. 27 - Prob. 12RQ
Ch. 27 - FSH is to estrogens as high levels of estrogens...Ch. 27 - 13. Which of the following does not add a...Ch. 27 - Prob. 11RQCh. 27 - Prob. 14RQCh. 27 - Prob. 15RQCh. 27 - Prob. 21RQCh. 27 - Prob. 16RQCh. 27 - Prob. 17RQCh. 27 - Prob. 18RQCh. 27 - Prob. 19RQCh. 27 - Prob. 20RQCh. 27 - 1. Gina Marciano, a 44-year-old mother of eight...Ch. 27 - Grant, a sexually active adolescent, visited his...Ch. 27 - Prob. 24RQCh. 27 - Prob. 25RQCh. 27 - Prob. 26RQCh. 27 - Prob. 1CCSCh. 27 - 23-Year-Old Female with Menstrual...Ch. 27 - Prob. 3CCSCh. 27 - 23-Year-Old Female with Menstrual Irregularity...Ch. 27 - 23-Year-Old Female with Menstrual Irregularity...Ch. 27 - 23-Year-Old Female with Menstrual...
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