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Chapter 27, Problem 5CCS

23-Year-Old Female with Menstrual Irregularity

Jasmine Herrera, 23, has been referred to the endocrinology clinic. She is very overweight, with obvious acne and facial hair. She complains of irregular menstrual cycles. “My husband and I want to use the rhythm method," she says, “but I don’t have any rhythm!”

Chapter 27, Problem 5CCS, 23-Year-Old Female with Menstrual Irregularity Jasmine Herrera, 23, has been referred to the

5. Jasmine’s blood tests reveal very high levels of androgens. She is diagnosed with polycystic ovary syndrome (PCOS). In this syndrome, the woman develops high levels of androgens and many vesicular follicles, but has reduced fertility because few follicles are ovulated and the timing of their release is unpredictable. Part of the profile of PCOS is that LH levels are high. How would this lead to androgen excess, and what clinical evidence of androgen excess does Jasmine have?

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