Fundamentals of Anatomy & Physiology (11th Edition)
Fundamentals of Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134477336
Author: Martini
Publisher: PEARSON
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Chapter 27, Problem 2CC
Summary Introduction

To determine:

The cause of the sensation of a “frog jumping around” in Marquis chest and dizziness

Introduction:

 Hypokalemia is a disorder in which the potassium concentration of the blood is low. The potassium ion is very essential in the body as it is employed in the ion transport channels and is also signification in the muscular contraction. The potassium level of the body is controlled by the kidney.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

Chapter 27 Solutions

Fundamentals of Anatomy & Physiology (11th Edition)

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