Lehninger Principles of Biochemistry (Instructor's)
Lehninger Principles of Biochemistry (Instructor's)
7th Edition
ISBN: 9781319117689
Author: nelson
Publisher: MAC HIGHER
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Chapter 27, Problem 21P
Summary Introduction

To calculate: The DNA required to encode 10 proteins by bacteriophage ϕ×174 .

Introduction:

The proteins are the macromolecules which are comprised of amino acids linked together by peptide or amide bond. Each of the amino acids is coded by three nucleotide bases. Bacteriophage ϕ×174 genome include 10 proteins, which are encoded by 5386 bp.. The size of the proteins and number of amino acid residues is different.

Summary Introduction

To explain: How the size of ϕ×174 genome can be reconciled with its the protein capacity.

Introduction:

The bacteriophage ϕ×174 is a single-stranded DNA virus with circular DNA comprised of 5,386 bp . The genome encodes for 10 proteins of varying length. The total number of amino acids in 10 proteins is 1,928 .

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a. The change in the Gibbs energy of a certain constant pressure process is found to fit the expression: AG-85.1 J mol −1 +36.5 J mol ¹K-1 × T A. Calculate the value of AS for the process. B. Next, use the Gibbs-Helmholtz equation: (a(AG/T)) ΔΗ - T2 to calculate the value of AH for the process.
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