Brock Biology of Microorganisms (15th Edition)
15th Edition
ISBN: 9780134261928
Author: Michael T. Madigan, Kelly S. Bender, Daniel H. Buckley, W. Matthew Sattley, David A. Stahl
Publisher: PEARSON
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Textbook Question
Chapter 26.9, Problem 1MQ
- In what ways does the classical pathway of complement activation differ from the mannose-binding lectin and alternative pathways?
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Chapter 26 Solutions
Brock Biology of Microorganisms (15th Edition)
Ch. 26.1 - What major class of immune cells mediates an...Ch. 26.1 - Prob. 2MQCh. 26.1 - Compare and contrast the major features of innate...Ch. 26.2 - Describe host tissue specificity for pathogens.Ch. 26.2 - Identify physical and chemical barriers to...Ch. 26.2 - What other factors may control the outcome of an...Ch. 26.2 - Identify at least four mechanisms by which a...Ch. 26.3 - Describe the circulation of a leukocyte from the...Ch. 26.3 - What soluble molecules determine whether a...Ch. 26.3 - Cells involved in innate and adaptive immunity...
Ch. 26.4 - How does the development of B, T, and NK cells...Ch. 26.4 - Distinguish between the primary lymphoid organs...Ch. 26.4 - Leukocytes are differentiated white blood cells...Ch. 26.5 - Although technically not part of the immune...Ch. 26.5 - Describe the mechanisms by which circulating...Ch. 26.5 - Pathogens may colonize host tissues when...Ch. 26.6 - Identify a PAMP shared by a group of...Ch. 26.6 - Outline the general features of a signal...Ch. 26.6 - Innate recognition of common pathogens occurs...Ch. 26.7 - Identify the mechanism used by phagocytes to...Ch. 26.7 - Describe several reasons why phagocytes are not...Ch. 26.7 - Phagocytosis is the engulfing of infectious...Ch. 26.8 - Prob. 1MQCh. 26.8 - Identify the major symptoms of localized...Ch. 26.8 - Fever and inflammation, characterized by pain,...Ch. 26.9 - In what ways does the classical pathway of...Ch. 26.9 - What is opsonization, and how does opsonization...Ch. 26.9 - Why are the mannose-binding lectin and alternative...Ch. 26.9 - The complement system is composed of soluble...Ch. 26.10 - Prob. 1MQCh. 26.10 - Prob. 2MQCh. 26.10 - Prob. 1CRCh. 26 - Prob. 1AQCh. 26 - Describe the potential problems that would arise...Ch. 26 - Prob. 3AQCh. 26 - Prob. 4AQ
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- The classical complement pathway involves activation of the complement proteins in which of the following manners? 1) C3b binds to the microbial surface, with factors B, D, and P 2) C1 binds to antibodies bound to the microbe's surface 3) Fungal mannose sugars trigger complement proteins in the blood 4) C3b binds to antibodies bound to the microbial surfacearrow_forwardDescribe the initiation and activation of classical complement pathway.arrow_forwardDescribe briefly the three effector functions of complement activation that result from the initial event of complement protein binding to peptidoglycans or LPSarrow_forward
- What clinical symptoms can an inherited deficiency in complement components C3 or C4 lead to?arrow_forwardWhat are TLRS? How does this work to ensure to prevent pathogens to cause diseases? Where are the locations of each TLRS? What are they exactly detecting specifically? How are cellular behavior changing after they detect pathogens via TLRS? How does complement get activated? Please explain three pathways of complement activation and end results of complement activation.arrow_forwardDistinguish between alternative complement pathway and Lectin pathway.arrow_forward
- Complement receptors and Fc receptors both contribute to removal of immune complexes from the circulation. Surprisingly, individuals with defects in the early components of the classical complement cascade (i.e., C1, C2, or C4) suffer from an autoimmune type of kidney damage, rather than from an immunodeficiency leading to increased susceptibility to infections. Why do these complement defects lead to autoimmune kidney damage?arrow_forwardWhy is complement low in lupus?arrow_forwardDescribe the mechanism of the classical complement pathway and discuss the critical role that the split products of C3 and other complement proteins play in the elimination of bacteria.arrow_forward
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